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D. E. Shaw & Co., Inc.
> AVGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2009 | AVIGEN INC \DE | AVGN | 150,935 | -81,792 | 225,000 | -82,000 | $1.49 |
| 06/30/2009 | AVIGEN INC \DE | AVGN | 232,727 | 104,411 | 307,000 | 209,000 | $1.32 |
| 03/31/2009 | AVIGEN INC \DE | AVGN | 239,203 | 110,887 | 291,000 | 193,000 | $1.22 |
| 12/31/2008 | AVIGEN INC \DE | AVGN | 128,316 | 95,182 | 98,000 | -35,000 | $0.76 |
| 09/30/2008 | AVIGEN INC \DE | AVGN | 33,134 | 33,134 | 133,000 | 133,000 | $4.01 |
| 06/30/2003 | AVIGEN INC \DE | AVGN | 0 | -25,335 | 0 | -74,000 | |
| 03/31/2003 | AVIGEN INC \DE | AVGN | 25,335 | -9,865 | 74,000 | -205,000 | $2.92 |
| 12/31/2002 | AVIGEN INC \DE | AVGN | 0 | -35,200 | 0 | -279,000 | |
| 09/30/2002 | AVIGEN INC \DE | AVGN | 35,200 | 7,900 | 279,000 | 22,000 | $7.93 |
| 06/30/2002 | AVIGEN INC \DE | AVGN | 27,300 | -17,000 | 257,000 | -235,000 | $9.41 |
| 03/31/2002 | AVIGEN INC \DE | AVGN | 44,300 | 8,900 | 492,000 | 85,000 | $11.11 |
| 12/31/2001 | AVIGEN INC \DE | AVGN | 35,400 | -14,400 | 407,000 | -276,000 | $11.50 |
| 09/30/2001 | AVIGEN INC \DE | AVGN | 49,800 | 26,800 | 683,000 | 188,000 | $13.71 |
| 06/30/2001 | AVIGEN INC \DE | AVGN | 23,000 | 11,600 | 495,000 | 356,000 | $21.52 |
| 03/31/2001 | AVIGEN INC \DE | AVGN | 11,400 | 1,200 | 139,000 | -73,000 | $12.19 |
| 12/31/2000 | AVIGEN INC \DE | AVGN | 10,200 | 10,200 | 212,000 | 212,000 | $20.78 |
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