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PADCO ADVISORS INC /MD NEW
> CYPB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2010 | CYPRESS BIOSCIENCE INC | CYPB | 0 | -1,871 | 0 | -4,000 | |
| 09/30/2010 | CYPRESS BIOSCIENCE INC | CYPB | 0 | -1,871 | 0 | -4,000 | |
| 09/30/2010 | CYPRESS BIOSCIENCE INC | CYPB | 0 | -1,871 | 0 | -4,000 | |
| 06/30/2010 | CYPRESS BIOSCIENCE INC | CYPB | 1,871 | 43 | 4,000 | -7,000 | $2.14 |
| 03/31/2010 | CYPRESS BIOSCIENCE INC | CYPB | 1,408 | -420 | 7,000 | -4,000 | $4.97 |
| 12/31/2009 | CYPRESS BIOSCIENCE INC | CYPB | 1,828 | 130 | 11,000 | -3,000 | $6.02 |
| 09/30/2009 | CYPRESS BIOSCIENCE INC | CYPB | 1,698 | 673 | 14,000 | 4,000 | $8.24 |
| 06/30/2009 | CYPRESS BIOSCIENCE INC | CYPB | 1,025 | -813 | 10,000 | -3,000 | $9.76 |
| 03/31/2009 | CYPRESS BIOSCIENCE INC | CYPB | 1,838 | -842 | 13,000 | -5,000 | $7.07 |
| 12/31/2008 | CYPRESS BIOSCIENCE INC | CYPB | 2,680 | 2,680 | 18,000 | 18,000 | $6.72 |
| 09/30/2008 | CYPRESS BIOSCIENCE INC | CYPB | 1,980 | -8,289 | 15,000 | -59,000 | $7.58 |
| 06/30/2008 | CYPRESS BIOSCIENCE INC | CYPB | 10,269 | 6,109 | 74,000 | 44,000 | $7.21 |
| 03/31/2008 | CYPRESS BIOSCIENCE INC | CYPB | 4,160 | -290 | 30,000 | -19,000 | $7.21 |
| 12/31/2007 | CYPRESS BIOSCIENCE INC | CYPB | 4,450 | 2,130 | 49,000 | 17,000 | $11.01 |
| 09/30/2007 | CYPRESS BIOSCIENCE INC | CYPB | 2,320 | 2,320 | 32,000 | 32,000 | $13.79 |
| 09/30/2006 | CYPRESS BIOSCIENCE INC | CYPB | 0 | -2,950 | 0 | -41,000 | |
| 09/30/2004 | CYPRESS BIOSCIENCE INC | CYPB | 0 | -2,950 | 0 | -41,000 | |
| 06/30/2004 | CYPRESS BIOSCIENCE INC | CYPB | 2,950 | 2,950 | 41,000 | 41,000 | $13.90 |
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