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NorthCoast Asset Management LLC
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,113 | -13,567 | 565,000 | -2,798,000 | $181.50 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 16,680 | 10,028 | 3,363,000 | 1,791,000 | $201.62 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,652 | -14,447 | 1,572,000 | -4,169,000 | $236.32 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 21,099 | 14,354 | 5,741,000 | 3,783,000 | $272.10 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,745 | -1,342 | 1,958,000 | 34,000 | $290.29 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 8,087 | 8,087 | 1,924,000 | 1,924,000 | $237.91 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -6,327 | 0 | -1,160,000 | |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,327 | 247 | 1,160,000 | 42,000 | $183.34 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,080 | -806 | 1,118,000 | -23,000 | $183.88 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,886 | 3,328 | 1,141,000 | 455,000 | $165.70 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,558 | -76 | 686,000 | 68,000 | $192.80 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,634 | 76 | 618,000 | 38,000 | $170.06 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,558 | -912 | 580,000 | -90,000 | $163.01 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,470 | 0 | 670,000 | -10,000 | $149.89 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,470 | -1,599 | 680,000 | -102,000 | $152.13 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,069 | 6,069 | 782,000 | 782,000 | $128.85 |
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