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BAKER BROS. ADVISORS LP
> DSGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Design Therapeutics, Inc. | DSGN | 500,000 | -192,131 | 3,150,000,000 | -3,951,264,000 | $6,300.00 |
| 12/31/2022 | Design Therapeutics, Inc. | DSGN | 692,131 | -744,505 | 7,101,264,000 | 7,077,243,000 | $10,260.00 |
| 09/30/2022 | Design Therapeutics, Inc. | DSGN | 1,436,636 | 0 | 24,021,000 | 3,908,000 | $16.72 |
| 06/30/2022 | Design Therapeutics, Inc. | DSGN | 1,436,636 | 0 | 20,113,000 | -3,089,000 | $14.00 |
| 03/31/2022 | Design Therapeutics, Inc. | DSGN | 1,436,636 | 0 | 23,202,000 | -7,556,000 | $16.15 |
| 12/31/2021 | Design Therapeutics, Inc. | DSGN | 1,436,636 | 0 | 30,758,000 | 9,654,000 | $21.41 |
| 09/30/2021 | Design Therapeutics, Inc. | DSGN | 1,436,636 | 0 | 21,104,000 | -7,471,000 | $14.69 |
| 06/30/2021 | Design Therapeutics, Inc. | DSGN | 1,436,636 | 0 | 28,575,000 | -14,380,000 | $19.89 |
| 03/31/2021 | Design Therapeutics, Inc. | DSGN | 1,436,636 | 1,436,636 | 42,955,000 | 42,955,000 | $29.90 |
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