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BAKER BROS. ADVISORS LP
> HZNP
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Horizon Therapeutics Public Ltd Co | HZNP | 0 | -969,727 | 0 | -110,354,933,000 | |
| 12/31/2022 | Horizon Therapeutics Public Ltd Co | HZNP | 969,727 | 0 | 110,354,933,000 | 110,294,917,000 | $113,800.00 |
| 09/30/2022 | Horizon Therapeutics Public Ltd Co | HZNP | 969,727 | -178,777 | 60,016,000 | -31,589,000 | $61.89 |
| 06/30/2022 | Horizon Therapeutics Public Ltd Co | HZNP | 1,148,504 | 249,662 | 91,605,000 | -2,962,000 | $79.76 |
| 03/31/2022 | Horizon Therapeutics Public Ltd Co | HZNP | 898,842 | 299,732 | 94,567,000 | 30,007,000 | $105.21 |
| 12/31/2021 | Horizon Therapeutics Public Ltd Co | HZNP | 599,110 | 0 | 64,560,000 | -1,067,000 | $107.76 |
| 09/30/2021 | Horizon Therapeutics Public Ltd Co | HZNP | 599,110 | 0 | 65,627,000 | 9,526,000 | $109.54 |
| 06/30/2021 | Horizon Therapeutics Public Ltd Co | HZNP | 599,110 | 0 | 56,101,000 | 959,000 | $93.64 |
| 03/31/2021 | Horizon Therapeutics Public Ltd Co | HZNP | 599,110 | 0 | 55,142,000 | 11,317,000 | $92.04 |
| 12/31/2020 | Horizon Therapeutics Public Ltd Co | HZNP | 599,110 | -67,390 | 43,825,000 | -7,949,000 | $73.15 |
| 09/30/2020 | Horizon Therapeutics Public Ltd Co | HZNP | 666,500 | 466,500 | 51,774,000 | 40,658,000 | $77.68 |
| 06/30/2020 | Horizon Therapeutics Public Ltd Co | HZNP | 200,000 | 0 | 11,116,000 | 5,192,000 | $55.58 |
| 03/31/2020 | Horizon Therapeutics Public Ltd Co | HZNP | 200,000 | 200,000 | 5,924,000 | 5,924,000 | $29.62 |
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