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BAKER BROS. ADVISORS LP
> ARGX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | ARGENX SE | ARGX | 280,159 | 0 | 109,186,367,000 | 3,053,733,000 | $389,730.00 |
| 12/31/2022 | ARGENX SE | ARGX | 280,159 | 0 | 106,132,634,000 | 106,033,724,000 | $378,830.00 |
| 09/30/2022 | ARGENX SE | ARGX | 280,159 | -839,398 | 98,910,000 | -325,268,000 | $353.05 |
| 06/30/2022 | ARGENX SE | ARGX | 1,119,557 | 0 | 424,178,000 | 71,170,000 | $378.88 |
| 03/31/2022 | ARGENX SE | ARGX | 1,119,557 | 0 | 353,008,000 | -39,050,000 | $315.31 |
| 12/31/2021 | ARGENX SE | ARGX | 1,119,557 | 0 | 392,058,000 | 53,952,000 | $350.19 |
| 09/30/2021 | ARGENX SE | ARGX | 1,119,557 | 0 | 338,106,000 | 1,041,000 | $302.00 |
| 06/30/2021 | ARGENX SE | ARGX | 1,119,557 | 0 | 337,065,000 | 28,750,000 | $301.07 |
| 03/31/2021 | ARGENX SE | ARGX | 1,119,557 | 100,000 | 308,315,000 | 8,473,000 | $275.39 |
| 12/31/2020 | ARGENX SE | ARGX | 1,019,557 | 0 | 299,842,000 | 32,188,000 | $294.09 |
| 09/30/2020 | ARGENX SE | ARGX | 1,019,557 | 0 | 267,654,000 | 38,019,000 | $262.52 |
| 06/30/2020 | ARGENX SE | ARGX | 1,019,557 | 0 | 229,635,000 | 95,329,000 | $225.23 |
| 03/31/2020 | ARGENX SE | ARGX | 1,019,557 | 0 | 134,306,000 | -29,353,000 | $131.73 |
| 12/31/2019 | ARGENX SE | ARGX | 1,019,557 | 0 | 163,659,000 | 47,470,000 | $160.52 |
| 09/30/2019 | ARGENX SE | ARGX | 1,019,557 | 0 | 116,189,000 | -28,160,000 | $113.96 |
| 06/30/2019 | ARGENX SE | ARGX | 1,019,557 | 0 | 144,349,000 | 17,068,000 | $141.58 |
| 03/31/2019 | ARGENX SE | ARGX | 1,019,557 | 0 | 127,281,000 | 29,332,000 | $124.84 |
| 12/31/2018 | ARGENX SE | ARGX | 1,019,557 | 0 | 97,949,000 | 20,626,000 | $96.07 |
| 09/30/2018 | ARGENX SE | ARGX | 1,019,557 | 57,803 | 77,323,000 | -2,368,000 | $75.84 |
| 06/30/2018 | ARGENX SE | ARGX | 961,754 | 0 | 79,691,000 | 18,966,000 | $82.86 |
| 12/31/2017 | ARGENX SE | ARGX | 961,754 | 861,754 | 60,725,000 | 58,464,000 | $63.14 |
| 09/30/2017 | ARGENX SE | ARGX | 100,000 | 0 | 2,261,000 | 140,000 | $22.61 |
| 06/30/2017 | ARGENX SE | ARGX | 100,000 | 100,000 | 2,121,000 | 2,121,000 | $21.21 |
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