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BAKER BROS. ADVISORS LP
> ASND
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Ascendis Pharma A/S | ASND | 0 | -4,954,855 | 0 | -605,136,441,000 | |
| 12/31/2022 | Ascendis Pharma A/S | ASND | 4,954,855 | 102,200 | 605,136,441,000 | 604,635,356,000 | $122,130.00 |
| 09/30/2022 | Ascendis Pharma A/S | ASND | 4,852,655 | 0 | 501,085,000 | 49,982,000 | $103.26 |
| 06/30/2022 | Ascendis Pharma A/S | ASND | 4,852,655 | 311,051 | 451,103,000 | -81,900,000 | $92.96 |
| 03/31/2022 | Ascendis Pharma A/S | ASND | 4,541,604 | 0 | 533,003,000 | -77,979,000 | $117.36 |
| 12/31/2021 | Ascendis Pharma A/S | ASND | 4,541,604 | 0 | 610,982,000 | -112,904,000 | $134.53 |
| 09/30/2021 | Ascendis Pharma A/S | ASND | 4,541,604 | 1,001,334 | 723,886,000 | 258,163,000 | $159.39 |
| 06/30/2021 | Ascendis Pharma A/S | ASND | 3,540,270 | 0 | 465,723,000 | 9,453,000 | $131.55 |
| 03/31/2021 | Ascendis Pharma A/S | ASND | 3,540,270 | 0 | 456,270,000 | -134,176,000 | $128.88 |
| 12/31/2020 | Ascendis Pharma A/S | ASND | 3,540,270 | 0 | 590,446,000 | 44,112,000 | $166.78 |
| 09/30/2020 | Ascendis Pharma A/S | ASND | 3,540,270 | 150,000 | 546,334,000 | 44,913,000 | $154.32 |
| 06/30/2020 | Ascendis Pharma A/S | ASND | 3,390,270 | 0 | 501,421,000 | 119,643,000 | $147.90 |
| 03/31/2020 | Ascendis Pharma A/S | ASND | 3,390,270 | 0 | 381,778,000 | -89,876,000 | $112.61 |
| 12/31/2019 | Ascendis Pharma A/S | ASND | 3,390,270 | 0 | 471,654,000 | 145,103,000 | $139.12 |
| 09/30/2019 | Ascendis Pharma A/S | ASND | 3,390,270 | 0 | 326,551,000 | -63,839,000 | $96.32 |
| 06/30/2019 | Ascendis Pharma A/S | ASND | 3,390,270 | 0 | 390,390,000 | -8,645,000 | $115.15 |
| 03/31/2019 | Ascendis Pharma A/S | ASND | 3,390,270 | 552,918 | 399,035,000 | 221,275,000 | $117.70 |
| 12/31/2018 | Ascendis Pharma A/S | ASND | 2,837,352 | 0 | 177,760,000 | -23,295,000 | $62.65 |
| 09/30/2018 | Ascendis Pharma A/S | ASND | 2,837,352 | 0 | 201,055,000 | 12,314,000 | $70.86 |
| 06/30/2018 | Ascendis Pharma A/S | ASND | 2,837,352 | 218,534 | 188,741,000 | 83,831,000 | $66.52 |
| 12/31/2017 | Ascendis Pharma A/S | ASND | 2,618,818 | 269,978 | 104,910,000 | 19,765,000 | $40.06 |
| 09/30/2017 | Ascendis Pharma A/S | ASND | 2,348,840 | 597,377 | 85,145,000 | 36,524,000 | $36.25 |
| 06/30/2017 | Ascendis Pharma A/S | ASND | 1,751,463 | 400,000 | 48,621,000 | 10,780,000 | $27.76 |
| 03/31/2017 | Ascendis Pharma A/S | ASND | 1,351,463 | 328,197 | 37,841,000 | 17,130,000 | $28.00 |
| 12/31/2016 | Ascendis Pharma A/S | ASND | 1,023,266 | 277,745 | 20,711,000 | 5,726,000 | $20.24 |
| 09/30/2016 | Ascendis Pharma A/S | ASND | 745,521 | 0 | 14,985,000 | 5,092,000 | $20.10 |
| 06/30/2016 | Ascendis Pharma A/S | ASND | 745,521 | 240,000 | 9,893,000 | 516,000 | $13.27 |
| 03/31/2016 | Ascendis Pharma A/S | ASND | 505,521 | 0 | 9,377,000 | 116,000 | $18.55 |
| 12/31/2015 | Ascendis Pharma A/S | ASND | 505,521 | 505,521 | 9,261,000 | 9,261,000 | $18.32 |
| 09/30/2015 | Ascendis Pharma A/S | ASND | 435,540 | 435,540 | 7,709,000 | 7,709,000 | $17.70 |
| 06/30/2015 | Ascendis Pharma A/S | ASND | 100,000 | 100,000 | 1,768,000 | 1,768,000 | $17.68 |
| 03/31/2015 | Ascendis Pharma A/S | ASND | 100,000 | 100,000 | 1,735,000 | 1,735,000 | $17.35 |
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