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CITADEL ADVISORS LLC
> AVRO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AVROBIO, Inc. | AVRO | 506,354 | -76,615 | 481,087,000 | 65,488,000 | $950.10 |
| 12/31/2022 | AVROBIO, Inc. | AVRO | 582,969 | 70,787 | 415,599,000 | 415,270,000 | $712.90 |
| 09/30/2022 | AVROBIO, Inc. | AVRO | 512,182 | -179,298 | 329,000 | -307,000 | $0.64 |
| 06/30/2022 | AVROBIO, Inc. | AVRO | 691,480 | 73,452 | 636,000 | -180,000 | $0.92 |
| 03/31/2022 | AVROBIO, Inc. | AVRO | 618,028 | 95,619 | 816,000 | -1,195,000 | $1.32 |
| 12/31/2021 | AVROBIO, Inc. | AVRO | 522,409 | -557,919 | 2,011,000 | -4,017,000 | $3.85 |
| 09/30/2021 | AVROBIO, Inc. | AVRO | 1,080,328 | -247,258 | 6,028,000 | -5,775,000 | $5.58 |
| 06/30/2021 | AVROBIO, Inc. | AVRO | 1,327,586 | -118,649 | 11,803,000 | -6,549,000 | $8.89 |
| 03/31/2021 | AVROBIO, Inc. | AVRO | 1,446,235 | -208,472 | 18,352,000 | -4,715,000 | $12.69 |
| 12/31/2020 | AVROBIO, Inc. | AVRO | 1,654,707 | -178,907 | 23,067,000 | -807,000 | $13.94 |
| 09/30/2020 | AVROBIO, Inc. | AVRO | 1,833,614 | -48,069 | 23,874,000 | -8,961,000 | $13.02 |
| 06/30/2020 | AVROBIO, Inc. | AVRO | 1,881,683 | -72,997 | 32,835,000 | 2,420,000 | $17.45 |
| 03/31/2020 | AVROBIO, Inc. | AVRO | 1,954,680 | 266,758 | 30,415,000 | -3,563,000 | $15.56 |
| 12/31/2019 | AVROBIO, Inc. | AVRO | 1,687,922 | 5,844 | 33,978,000 | 10,227,000 | $20.13 |
| 09/30/2019 | AVROBIO, Inc. | AVRO | 1,682,078 | 75,931 | 23,751,000 | -2,365,000 | $14.12 |
| 06/30/2019 | AVROBIO, Inc. | AVRO | 1,606,147 | -6,774 | 26,116,000 | -9,449,000 | $16.26 |
| 03/31/2019 | AVROBIO, Inc. | AVRO | 1,612,921 | 250,266 | 35,565,000 | 12,877,000 | $22.05 |
| 12/31/2018 | AVROBIO, Inc. | AVRO | 1,362,655 | -128,679 | 22,688,000 | -54,667,000 | $16.65 |
| 09/30/2018 | AVROBIO, Inc. | AVRO | 1,491,334 | -301,380 | 77,355,000 | 26,155,000 | $51.87 |
| 06/30/2018 | AVROBIO, Inc. | AVRO | 1,792,714 | 1,792,714 | 51,200,000 | 51,200,000 | $28.56 |
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