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Bank of New York Mellon Corp
> RYTM
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 187,796 | 161,070 | 3,096,756,000 | 2,619,965,000 | $16,490.00 |
| 03/31/2023 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 26,726 | -5,557 | 476,791,000 | -463,290,000 | $17,839.97 |
| 12/31/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 32,283 | 32,283 | 940,081,000 | 940,081,000 | $29,120.00 |
| 09/30/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 0 | -21,495 | 0 | -89,000 | |
| 06/30/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 21,495 | -130,854 | 89,000 | -1,667,000 | $4.14 |
| 03/31/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 152,349 | -4,569 | 1,756,000 | 190,000 | $11.53 |
| 12/31/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 156,918 | 495 | 1,566,000 | -477,000 | $9.98 |
| 09/30/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 156,423 | 16,391 | 2,043,000 | -698,000 | $13.06 |
| 06/30/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 140,032 | 9,610 | 2,741,000 | -1,137,000 | $19.57 |
| 03/31/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 0 | -130,422 | 0 | -3,878,000 | |
| 12/31/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 130,422 | 5,734 | 3,878,000 | 1,176,000 | $29.73 |
| 09/30/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 124,688 | -1,618 | 2,702,000 | -115,000 | $21.67 |
| 06/30/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 126,306 | 10,476 | 2,817,000 | 1,054,000 | $22.30 |
| 03/31/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 115,830 | 5,890 | 1,763,000 | -761,000 | $15.22 |
| 12/31/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 109,940 | 24,510 | 2,524,000 | 680,000 | $22.96 |
| 09/30/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 85,430 | -629 | 1,844,000 | -50,000 | $21.58 |
| 06/30/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 86,059 | 16,507 | 1,894,000 | -12,000 | $22.01 |
| 03/31/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 69,552 | 2,464 | 1,906,000 | 102,000 | $27.40 |
| 12/31/2018 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 67,088 | 6,814 | 1,804,000 | 45,000 | $26.89 |
| 09/30/2018 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 60,274 | 22,481 | 1,759,000 | 578,000 | $29.18 |
| 06/30/2018 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 37,793 | 13,462 | 1,181,000 | 696,000 | $31.25 |
| 03/31/2018 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 24,331 | 6,323 | 485,000 | -38,000 | $19.93 |
| 12/31/2017 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 18,008 | 18,008 | 523,000 | 523,000 | $29.04 |
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