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ADAGE CAPITAL PARTNERS GP, L.L.C.
> INZY
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Inozyme Pharma, Inc. | INZY | 4,250,000 | -15,138 | 23,672,500,000 | -766,741,000 | $5,570.00 |
| 03/31/2023 | Inozyme Pharma, Inc. | INZY | 4,265,138 | 1,668,466 | 24,439,241,000 | 24,432,282,000 | $5,730.00 |
| 09/30/2022 | Inozyme Pharma, Inc. | INZY | 2,596,672 | 50,000 | 6,959,000 | -5,189,000 | $2.68 |
| 06/30/2022 | Inozyme Pharma, Inc. | INZY | 2,546,672 | 800,000 | 12,148,000 | 5,004,000 | $4.77 |
| 03/31/2022 | Inozyme Pharma, Inc. | INZY | 1,746,672 | 147,644 | 7,144,000 | -3,761,000 | $4.09 |
| 12/31/2021 | Inozyme Pharma, Inc. | INZY | 1,599,028 | 131,200 | 10,905,000 | -6,107,000 | $6.82 |
| 09/30/2021 | Inozyme Pharma, Inc. | INZY | 1,467,828 | 179,156 | 17,012,000 | -4,947,000 | $11.59 |
| 06/30/2021 | Inozyme Pharma, Inc. | INZY | 1,288,672 | 199,000 | 21,959,000 | 383,000 | $17.04 |
| 03/31/2021 | Inozyme Pharma, Inc. | INZY | 1,089,672 | 193,000 | 21,576,000 | 3,069,000 | $19.80 |
| 12/31/2020 | Inozyme Pharma, Inc. | INZY | 896,672 | 96,672 | 18,507,000 | -2,525,000 | $20.64 |
| 09/30/2020 | Inozyme Pharma, Inc. | INZY | 800,000 | 800,000 | 21,032,000 | 21,032,000 | $26.29 |
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