News + Filings Holdings
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JANE STREET GROUP, LLC
> OPK
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | OPKO HEALTH, INC. | OPK | 535,649 | -104,160 | 1,162,358,000 | 362,597,000 | $2,170.00 |
| 12/31/2022 | OPKO HEALTH, INC. | OPK | 639,809 | -446,924 | 799,761,000 | 797,707,000 | $1,250.00 |
| 09/30/2022 | OPKO HEALTH, INC. | OPK | 1,086,733 | 489,131 | 2,054,000 | 542,000 | $1.89 |
| 06/30/2022 | OPKO HEALTH, INC. | OPK | 597,602 | 58,269 | 1,512,000 | -343,000 | $2.53 |
| 03/31/2022 | OPKO HEALTH, INC. | OPK | 539,333 | -802,895 | 1,855,000 | -4,601,000 | $3.44 |
| 12/31/2021 | OPKO HEALTH, INC. | OPK | 1,342,228 | 800,167 | 6,456,000 | 4,261,000 | $4.81 |
| 06/30/2021 | OPKO HEALTH, INC. | OPK | 542,061 | -166,505 | 2,195,000 | -844,000 | $4.05 |
| 03/31/2021 | OPKO HEALTH, INC. | OPK | 708,566 | 437,386 | 3,039,000 | 1,968,000 | $4.29 |
| 12/31/2020 | OPKO HEALTH, INC. | OPK | 271,180 | -971,863 | 1,071,000 | -3,167,000 | $3.95 |
| 06/30/2020 | OPKO HEALTH, INC. | OPK | 1,243,043 | 530,122 | 4,238,000 | 3,284,000 | $3.41 |
| 03/31/2020 | OPKO HEALTH, INC. | OPK | 712,921 | 218,610 | 954,000 | 228,000 | $1.34 |
| 12/31/2019 | OPKO HEALTH, INC. | OPK | 494,311 | 431,616 | 726,000 | 595,000 | $1.47 |
| 09/30/2019 | OPKO HEALTH, INC. | OPK | 62,695 | -197,024 | 131,000 | -502,000 | $2.09 |
| 06/30/2019 | OPKO HEALTH, INC. | OPK | 259,719 | -140,562 | 633,000 | -412,000 | $2.44 |
| 03/31/2019 | OPKO HEALTH, INC. | OPK | 400,281 | -131,233 | 1,045,000 | -555,000 | $2.61 |
| 12/31/2018 | OPKO HEALTH, INC. | OPK | 531,514 | 451,772 | 1,600,000 | 1,324,000 | $3.01 |
| 09/30/2018 | OPKO HEALTH, INC. | OPK | 79,742 | -69,592 | 276,000 | -426,000 | $3.46 |
| 06/30/2018 | OPKO HEALTH, INC. | OPK | 149,334 | -225,985 | 702,000 | -488,000 | $4.70 |
| 03/31/2018 | OPKO HEALTH, INC. | OPK | 375,319 | 18,741 | 1,190,000 | -556,000 | $3.17 |
| 12/31/2017 | OPKO HEALTH, INC. | OPK | 356,578 | 93,567 | 1,746,000 | -59,000 | $4.90 |
| 09/30/2017 | OPKO HEALTH, INC. | OPK | 263,011 | -75,560 | 1,805,000 | -423,000 | $6.86 |
| 06/30/2017 | OPKO HEALTH, INC. | OPK | 338,571 | -153,210 | 2,228,000 | -1,706,000 | $6.58 |
| 03/31/2017 | OPKO HEALTH, INC. | OPK | 491,781 | 223,535 | 3,934,000 | 1,439,000 | $8.00 |
| 12/31/2016 | OPKO HEALTH, INC. | OPK | 268,246 | -65,388 | 2,495,000 | -1,038,000 | $9.30 |
| 09/30/2016 | OPKO HEALTH, INC. | OPK | 333,634 | 234,647 | 3,533,000 | 2,608,000 | $10.59 |
| 06/30/2016 | OPKO HEALTH, INC. | OPK | 98,987 | 98,987 | 925,000 | 925,000 | $9.34 |
| 03/31/2016 | OPKO HEALTH, INC. | OPK | 357,105 | 277,687 | 3,710,000 | 2,917,000 | $10.39 |
| 12/31/2015 | OPKO HEALTH, INC. | OPK | 272,444 | -105,666 | 2,738,000 | -442,000 | $10.05 |
| 09/30/2015 | OPKO HEALTH, INC. | OPK | 378,110 | 298,692 | 3,180,000 | 2,387,000 | $8.41 |
| 06/30/2015 | OPKO HEALTH, INC. | OPK | 45,000 | -34,418 | 724,000 | -69,000 | $16.09 |
| 03/31/2015 | OPKO HEALTH, INC. | OPK | 39,195 | -89,289 | 555,000 | -642,000 | $14.16 |
| 12/31/2014 | OPKO HEALTH, INC. | OPK | 79,418 | -49,066 | 793,000 | -404,000 | $9.99 |
| 09/30/2014 | OPKO HEALTH, INC. | OPK | 0 | -218,006 | 0 | -1,927,000 | |
| 06/30/2014 | OPKO HEALTH, INC. | OPK | 218,006 | 89,522 | 1,927,000 | 730,000 | $8.84 |
| 03/31/2014 | OPKO HEALTH, INC. | OPK | 128,484 | 128,484 | 1,197,000 | 1,197,000 | $9.32 |
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