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STATE STREET CORP
> MNLO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2020 | VYNE Therapeutics Inc. | MNLO | 1,461,787 | 779,069 | 2,529,000 | 699,000 | $1.73 |
| 03/31/2020 | VYNE Therapeutics Inc. | MNLO | 682,718 | 420,994 | 1,830,000 | 616,000 | $2.68 |
| 12/31/2019 | VYNE Therapeutics Inc. | MNLO | 261,724 | 21,204 | 1,214,000 | 136,000 | $4.64 |
| 09/30/2019 | VYNE Therapeutics Inc. | MNLO | 240,520 | 31,998 | 1,078,000 | -171,000 | $4.48 |
| 06/30/2019 | VYNE Therapeutics Inc. | MNLO | 208,522 | 75,950 | 1,249,000 | 208,000 | $5.99 |
| 03/31/2019 | VYNE Therapeutics Inc. | MNLO | 132,572 | -50,849 | 1,041,000 | 285,000 | $7.85 |
| 12/31/2018 | VYNE Therapeutics Inc. | MNLO | 183,421 | 48,014 | 756,000 | -580,000 | $4.12 |
| 09/30/2018 | VYNE Therapeutics Inc. | MNLO | 135,407 | 41,769 | 1,336,000 | 577,000 | $9.87 |
| 06/30/2018 | VYNE Therapeutics Inc. | MNLO | 93,638 | 93,638 | 759,000 | 759,000 | $8.11 |
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