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STATE STREET CORP
> CRXX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2010 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 836,100 | 816,500 | 1,213,000 | 1,190,000 | $1.45 |
| 03/31/2010 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 19,600 | 0 | 23,000 | 7,000 | $1.17 |
| 12/31/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 19,600 | 0 | 16,000 | -11,000 | $0.82 |
| 09/30/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 19,600 | 0 | 27,000 | 11,000 | $1.38 |
| 06/30/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 19,600 | 0 | 16,000 | 4,000 | $0.82 |
| 03/31/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 19,600 | -5,700 | 12,000 | -4,000 | $0.61 |
| 12/31/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 25,300 | -300 | 16,000 | -67,000 | $0.63 |
| 09/30/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 25,600 | 0 | 83,000 | -8,000 | $3.24 |
| 06/30/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 25,600 | -5,042 | 91,000 | -14,000 | $3.55 |
| 03/31/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 30,642 | 0 | 105,000 | -31,000 | $3.43 |
| 12/31/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 30,642 | 0 | 136,000 | -56,000 | $4.44 |
| 09/30/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 30,642 | -500 | 192,000 | 0 | $6.27 |
| 06/30/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 31,142 | -388,092 | 192,000 | -2,738,000 | $6.17 |
| 03/31/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 419,234 | 419,234 | 2,930,000 | 2,930,000 | $6.99 |
| 12/31/2006 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -263,954 | 0 | -1,644,000 | |
| 09/30/2006 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 263,954 | 122,718 | 1,644,000 | 403,000 | $6.23 |
| 06/30/2006 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 141,236 | 141,236 | 1,241,000 | 1,241,000 | $8.79 |
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