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VANGUARD GROUP INC
> CRXX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2010 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 525,447 | 175,852 | 762,000 | 346,000 | $1.45 |
| 03/31/2010 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 349,595 | 164,153 | 416,000 | 262,000 | $1.19 |
| 12/31/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 185,442 | 19,100 | 154,000 | -79,000 | $0.83 |
| 09/30/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 166,342 | 34,720 | 233,000 | 125,000 | $1.40 |
| 06/30/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 131,622 | 0 | 108,000 | 26,000 | $0.82 |
| 03/31/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 131,622 | 0 | 82,000 | 0 | $0.62 |
| 12/31/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 131,622 | -102,245 | 82,000 | -673,000 | $0.62 |
| 09/30/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 233,867 | 233,041 | 755,000 | 522,377 | $3.23 |
| 06/30/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 826 | 193 | 232,623 | 48,473 | $281.63 |
| 03/31/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 633 | 633 | 184,150 | 184,150 | $290.92 |
| 12/31/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 802 | 802 | 180,606 | 180,606 | $225.19 |
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