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ORBIMED ADVISORS LLC
> REGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | REGENERON PHARMACEUTICALS, INC. | REGN | 13,500 | -10,500 | 9,700,290,000 | -10,019,790,000 | $718,540.00 |
| 03/31/2023 | REGENERON PHARMACEUTICALS, INC. | REGN | 24,000 | 24,000 | 19,720,080,000 | 19,720,080,000 | $821,670.00 |
| 09/30/2022 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -22,200 | 0 | -13,123,000 | |
| 06/30/2022 | REGENERON PHARMACEUTICALS, INC. | REGN | 22,200 | 22,200 | 13,123,000 | 13,123,000 | $591.13 |
| 09/30/2020 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -30,900 | 0 | -19,271,000 | |
| 06/30/2020 | REGENERON PHARMACEUTICALS, INC. | REGN | 30,900 | 13,700 | 19,271,000 | 10,872,000 | $623.66 |
| 03/31/2020 | REGENERON PHARMACEUTICALS, INC. | REGN | 17,200 | -192,100 | 8,399,000 | -70,189,000 | $488.31 |
| 12/31/2019 | REGENERON PHARMACEUTICALS, INC. | REGN | 209,300 | -18,800 | 78,588,000 | 15,313,000 | $375.48 |
| 09/30/2019 | REGENERON PHARMACEUTICALS, INC. | REGN | 228,100 | 12,300 | 63,275,000 | -4,270,000 | $277.40 |
| 06/30/2019 | REGENERON PHARMACEUTICALS, INC. | REGN | 215,800 | 1,000 | 67,545,000 | -20,656,000 | $313.00 |
| 03/31/2019 | REGENERON PHARMACEUTICALS, INC. | REGN | 214,800 | -7,300 | 88,201,000 | 5,247,000 | $410.62 |
| 12/31/2018 | REGENERON PHARMACEUTICALS, INC. | REGN | 222,100 | -172,300 | 82,954,000 | -76,399,000 | $373.50 |
| 09/30/2018 | REGENERON PHARMACEUTICALS, INC. | REGN | 394,400 | 21,900 | 159,353,000 | 30,844,000 | $404.04 |
| 06/30/2018 | REGENERON PHARMACEUTICALS, INC. | REGN | 372,500 | -590,400 | 128,509,000 | -203,075,000 | $344.99 |
| 03/31/2018 | REGENERON PHARMACEUTICALS, INC. | REGN | 962,900 | 108,300 | 331,584,000 | 10,289,000 | $344.36 |
| 12/31/2017 | REGENERON PHARMACEUTICALS, INC. | REGN | 854,600 | 281,830 | 321,295,000 | 65,198,000 | $375.96 |
| 09/30/2017 | REGENERON PHARMACEUTICALS, INC. | REGN | 572,770 | 106,000 | 256,097,000 | 26,848,000 | $447.12 |
| 06/30/2017 | REGENERON PHARMACEUTICALS, INC. | REGN | 466,770 | 88,600 | 229,249,000 | 82,704,000 | $491.14 |
| 03/31/2017 | REGENERON PHARMACEUTICALS, INC. | REGN | 378,170 | 22,870 | 146,545,000 | 16,118,000 | $387.51 |
| 12/31/2016 | REGENERON PHARMACEUTICALS, INC. | REGN | 355,300 | 0 | 130,427,000 | -12,411,000 | $367.09 |
| 09/30/2016 | REGENERON PHARMACEUTICALS, INC. | REGN | 355,300 | -154,600 | 142,838,000 | -35,234,000 | $402.02 |
| 06/30/2016 | REGENERON PHARMACEUTICALS, INC. | REGN | 509,900 | 509,900 | 178,072,000 | 178,072,000 | $349.23 |
| 03/31/2016 | REGENERON PHARMACEUTICALS, INC. | REGN | 533,000 | 50,000 | 192,115,000 | -70,091,000 | $360.44 |
| 12/31/2015 | REGENERON PHARMACEUTICALS, INC. | REGN | 483,000 | 263,200 | 262,206,000 | 224,605,000 | $542.87 |
| 09/30/2015 | REGENERON PHARMACEUTICALS, INC. | REGN | 487,700 | 267,900 | 226,849,000 | 189,248,000 | $465.14 |
| 06/30/2015 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -219,800 | 0 | -37,601,000 | |
| 03/31/2015 | REGENERON PHARMACEUTICALS, INC. | REGN | 421,800 | 202,000 | 190,434,000 | 152,833,000 | $451.48 |
| 12/31/2014 | REGENERON PHARMACEUTICALS, INC. | REGN | 390,200 | 170,400 | 160,080,000 | 122,479,000 | $410.25 |
| 09/30/2014 | REGENERON PHARMACEUTICALS, INC. | REGN | 369,600 | 149,800 | 133,248,000 | 95,647,000 | $360.52 |
| 06/30/2014 | REGENERON PHARMACEUTICALS, INC. | REGN | 326,600 | 106,800 | 92,255,000 | 54,654,000 | $282.47 |
| 03/31/2014 | REGENERON PHARMACEUTICALS, INC. | REGN | 539,000 | 319,200 | 161,851,000 | 124,250,000 | $300.28 |
| 12/31/2013 | REGENERON PHARMACEUTICALS, INC. | REGN | 738,800 | 519,000 | 203,347,000 | 165,746,000 | $275.24 |
| 09/30/2013 | REGENERON PHARMACEUTICALS, INC. | REGN | 513,100 | 293,300 | 160,534,000 | 122,933,000 | $312.87 |
| 06/30/2013 | REGENERON PHARMACEUTICALS, INC. | REGN | 351,100 | 131,300 | 78,955,000 | 41,354,000 | $224.88 |
| 03/31/2013 | REGENERON PHARMACEUTICALS, INC. | REGN | 241,800 | 22,000 | 42,654,000 | 5,053,000 | $176.40 |
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