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ORBIMED ADVISORS LLC
> EPIX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | ESSA Pharma Inc. | EPIX | 921,940 | -276,397 | 2,489,238,000 | -1,069,823,000 | $2,700.00 |
| 03/31/2023 | ESSA Pharma Inc. | EPIX | 1,198,337 | 833,037 | 3,559,061,000 | 2,638,505,000 | $2,970.00 |
| 12/31/2022 | ESSA Pharma Inc. | EPIX | 365,300 | -275,345 | 920,556,000 | 919,390,000 | $2,520.00 |
| 09/30/2022 | ESSA Pharma Inc. | EPIX | 640,645 | 640,645 | 1,166,000 | 1,166,000 | $1.82 |
| 03/31/2021 | ESSA Pharma Inc. | EPIX | 0 | -460,500 | 0 | -5,494,000 | |
| 12/31/2020 | ESSA Pharma Inc. | EPIX | 460,500 | -716,983 | 5,494,000 | -2,631,000 | $11.93 |
| 09/30/2020 | ESSA Pharma Inc. | EPIX | 1,177,483 | -294,370 | 8,125,000 | -1,000,000 | $6.90 |
| 06/30/2020 | ESSA Pharma Inc. | EPIX | 1,471,853 | 0 | 9,125,000 | 3,238,000 | $6.20 |
| 03/31/2020 | ESSA Pharma Inc. | EPIX | 1,471,853 | 0 | 5,887,000 | -2,208,000 | $4.00 |
| 12/31/2019 | ESSA Pharma Inc. | EPIX | 1,471,853 | 0 | 8,095,000 | 3,135,000 | $5.50 |
| 09/30/2019 | ESSA Pharma Inc. | EPIX | 1,471,853 | 1,471,853 | 4,960,000 | 4,960,000 | $3.37 |
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