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ORBIMED ADVISORS LLC
> ARGX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | ARGENX SE | ARGX | 32,600 | -11,900 | 12,705,198,000 | -3,874,612,000 | $389,730.00 |
| 03/31/2023 | ARGENX SE | ARGX | 44,500 | 28,300 | 16,579,810,000 | 10,442,764,000 | $372,580.00 |
| 12/31/2022 | ARGENX SE | ARGX | 16,200 | -253,500 | 6,137,046,000 | 6,041,828,000 | $378,830.00 |
| 09/30/2022 | ARGENX SE | ARGX | 269,700 | 75,700 | 95,218,000 | 21,715,000 | $353.05 |
| 06/30/2022 | ARGENX SE | ARGX | 194,000 | 24,200 | 73,503,000 | 19,963,000 | $378.88 |
| 03/31/2022 | ARGENX SE | ARGX | 169,800 | 169,800 | 53,540,000 | 53,540,000 | $315.31 |
| 06/30/2020 | ARGENX SE | ARGX | 0 | -28,591 | 0 | -3,766,000 | |
| 03/31/2020 | ARGENX SE | ARGX | 28,591 | -227,709 | 3,766,000 | -37,375,000 | $131.72 |
| 12/31/2019 | ARGENX SE | ARGX | 256,300 | -54,100 | 41,141,000 | 5,768,000 | $160.52 |
| 09/30/2019 | ARGENX SE | ARGX | 310,400 | 0 | 35,373,000 | -8,573,000 | $113.96 |
| 06/30/2019 | ARGENX SE | ARGX | 310,400 | -50,900 | 43,946,000 | -1,159,000 | $141.58 |
| 03/31/2019 | ARGENX SE | ARGX | 361,300 | -286,300 | 45,105,000 | -17,110,000 | $124.84 |
| 12/31/2018 | ARGENX SE | ARGX | 647,600 | -71,200 | 62,215,000 | 7,701,000 | $96.07 |
| 09/30/2018 | ARGENX SE | ARGX | 718,800 | 119,500 | 54,514,000 | 4,856,000 | $75.84 |
| 06/30/2018 | ARGENX SE | ARGX | 599,300 | 99,300 | 49,658,000 | 9,438,000 | $82.86 |
| 03/31/2018 | ARGENX SE | ARGX | 500,000 | 0 | 40,220,000 | 8,650,000 | $80.44 |
| 12/31/2017 | ARGENX SE | ARGX | 500,000 | 0 | 31,570,000 | 20,265,000 | $63.14 |
| 09/30/2017 | ARGENX SE | ARGX | 500,000 | 0 | 11,305,000 | 700,000 | $22.61 |
| 06/30/2017 | ARGENX SE | ARGX | 500,000 | 500,000 | 10,605,000 | 10,605,000 | $21.21 |
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