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HARDING LOEVNER LP
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,538,270 | -288,354 | 541,332,763,000 | -34,198,611,000 | $351,910.11 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,826,624 | 186,807 | 575,531,374,000 | 575,056,581,000 | $315,079.28 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,639,817 | -93,874 | 474,793,000 | -13,747,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,733,691 | -35,585 | 488,540,000 | 71,201,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,769,276 | -112,595 | 417,339,000 | 4,081,000 | $235.88 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,881,871 | -29,232 | 413,258,000 | 66,603,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,911,103 | -87,975 | 346,655,000 | -56,419,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,999,078 | 15,989 | 403,074,000 | -23,072,000 | $201.63 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,983,089 | -60,006 | 426,146,000 | -56,718,000 | $214.89 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,043,095 | 42,554 | 482,864,000 | -61,523,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,000,541 | -21,226 | 544,387,000 | -42,552,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,021,767 | -25,507 | 586,939,000 | 99,790,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,047,274 | -44,382 | 487,149,000 | 29,181,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,091,656 | -231,426 | 457,968,000 | 64,392,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,323,082 | 1,582,711 | 393,576,000 | 257,807,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 740,371 | -11,673 | 135,769,000 | -2,569,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 752,044 | 751,975 | 138,338,000 | 138,327,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 69 | 69 | 11,000 | 11,000 | $159.42 |
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