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TWO SIGMA INVESTMENTS, LP
> CTMX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | CytomX Therapeutics, Inc. | CTMX | 138,447 | -329,169 | 238,129,000 | -467,971,000 | $1,720.00 |
| 03/31/2023 | CytomX Therapeutics, Inc. | CTMX | 467,616 | -273,108 | 706,100,000 | -479,058,000 | $1,510.00 |
| 12/31/2022 | CytomX Therapeutics, Inc. | CTMX | 740,724 | 442,840 | 1,185,158,000 | 1,184,613,000 | $1,600.00 |
| 06/30/2022 | CytomX Therapeutics, Inc. | CTMX | 297,884 | -193,892 | 545,000 | -768,000 | $1.83 |
| 03/31/2022 | CytomX Therapeutics, Inc. | CTMX | 491,776 | 306,811 | 1,313,000 | 512,000 | $2.67 |
| 12/31/2021 | CytomX Therapeutics, Inc. | CTMX | 184,965 | 83,111 | 801,000 | 283,000 | $4.33 |
| 09/30/2021 | CytomX Therapeutics, Inc. | CTMX | 101,854 | 17,509 | 518,000 | -16,000 | $5.09 |
| 06/30/2021 | CytomX Therapeutics, Inc. | CTMX | 84,345 | -399,600 | 534,000 | -3,207,000 | $6.33 |
| 03/31/2021 | CytomX Therapeutics, Inc. | CTMX | 483,945 | -30,958 | 3,741,000 | 368,000 | $7.73 |
| 12/31/2020 | CytomX Therapeutics, Inc. | CTMX | 514,903 | 90,419 | 3,373,000 | 550,000 | $6.55 |
| 09/30/2020 | CytomX Therapeutics, Inc. | CTMX | 424,484 | 183,357 | 2,823,000 | 814,000 | $6.65 |
| 06/30/2020 | CytomX Therapeutics, Inc. | CTMX | 241,127 | 62,192 | 2,009,000 | 637,000 | $8.33 |
| 03/31/2020 | CytomX Therapeutics, Inc. | CTMX | 178,935 | -131,777 | 1,372,000 | -1,210,000 | $7.67 |
| 12/31/2019 | CytomX Therapeutics, Inc. | CTMX | 310,712 | 234,381 | 2,582,000 | 2,019,000 | $8.31 |
| 09/30/2019 | CytomX Therapeutics, Inc. | CTMX | 76,331 | -58,126 | 563,000 | -946,000 | $7.38 |
| 06/30/2019 | CytomX Therapeutics, Inc. | CTMX | 134,457 | 39,922 | 1,509,000 | 493,000 | $11.22 |
| 03/31/2019 | CytomX Therapeutics, Inc. | CTMX | 94,535 | -91,787 | 1,016,000 | -1,797,000 | $10.75 |
| 12/31/2018 | CytomX Therapeutics, Inc. | CTMX | 186,322 | -28,325 | 2,813,000 | -1,158,000 | $15.10 |
| 09/30/2018 | CytomX Therapeutics, Inc. | CTMX | 214,647 | -72,154 | 3,971,000 | -2,585,000 | $18.50 |
| 06/30/2018 | CytomX Therapeutics, Inc. | CTMX | 286,801 | 84,925 | 6,556,000 | 813,000 | $22.86 |
| 03/31/2018 | CytomX Therapeutics, Inc. | CTMX | 201,876 | 48,536 | 5,743,000 | 2,506,000 | $28.45 |
| 12/31/2017 | CytomX Therapeutics, Inc. | CTMX | 153,340 | 16,479 | 3,237,000 | 750,000 | $21.11 |
| 09/30/2017 | CytomX Therapeutics, Inc. | CTMX | 136,861 | 136,861 | 2,487,000 | 2,487,000 | $18.17 |
| 06/30/2017 | CytomX Therapeutics, Inc. | CTMX | 0 | -13,762 | 0 | -238,000 | |
| 03/31/2017 | CytomX Therapeutics, Inc. | CTMX | 13,762 | 13,762 | 238,000 | 238,000 | $17.29 |
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