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Invesco Ltd.
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,949,329 | 87,961 | 685,988,369,000 | 99,527,152,000 | $351,910.00 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,861,368 | 541,686 | 586,461,217,000 | 586,079,120,000 | $315,070.00 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,319,682 | 196,888 | 382,097,000 | 65,704,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,122,794 | -87,563 | 316,393,000 | 526,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,210,357 | 88,199 | 315,867,000 | 69,441,000 | $260.97 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,122,158 | -92,335 | 246,426,000 | 26,132,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,214,493 | 48,410 | 220,294,000 | -14,823,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,166,083 | 197,494 | 235,117,000 | 26,976,000 | $201.63 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 968,589 | -129,332 | 208,141,000 | -51,341,000 | $214.89 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,097,921 | -33,046 | 259,482,000 | -48,278,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,130,967 | 11,258 | 307,760,000 | -17,304,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,119,709 | -182,032 | 325,064,000 | 15,315,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,301,741 | 207,470 | 309,749,000 | 70,159,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,094,271 | -2,565,660 | 239,590,000 | -380,476,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,659,931 | -403,977 | 620,066,000 | -125,172,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,063,908 | 335,938 | 745,238,000 | 59,476,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,727,970 | 21,753 | 685,762,000 | 71,605,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,706,217 | -11,713 | 614,157,000 | -102,436,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,717,930 | -77,449 | 716,593,000 | 71,530,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,795,379 | 515,949 | 645,063,000 | 110,582,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,279,430 | 169,936 | 534,481,000 | 68,494,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,109,494 | 14,479 | 465,987,000 | -4,577,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,095,015 | -166,710 | 470,564,000 | 50,225,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,261,725 | 328,399 | 420,339,000 | 99,581,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,933,326 | 29,887 | 320,758,000 | 106,860,000 | $109.35 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,903,439 | -163,512 | 213,898,000 | -53,572,000 | $73.67 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,066,951 | -105 | 267,470,000 | 3,642,000 | $87.21 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,067,056 | 3,067,056 | 263,828,000 | 263,828,000 | $86.02 |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -4,251,208 | 0 | -534,929,000 | |
| 12/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,251,208 | 164,266 | 534,929,000 | 109,315,000 | $125.83 |
| 09/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,086,942 | 334,402 | 425,614,000 | -37,752,000 | $104.14 |
| 06/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,752,540 | 233,736 | 463,366,000 | 48,252,000 | $123.48 |
| 03/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,518,804 | 432,823 | 415,114,000 | 48,499,000 | $117.97 |
| 12/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,085,981 | 234,511 | 366,615,000 | 46,366,000 | $118.80 |
| 09/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,851,470 | -153,621 | 320,249,000 | 35,728,000 | $112.31 |
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