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CADIAN CAPITAL MANAGEMENT, LP
> BPMC
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Blueprint Medicines Corp | BPMC | 0 | -1,459,431 | 0 | -96,162,000 | |
| 09/30/2022 | Blueprint Medicines Corp | BPMC | 1,459,431 | -561,198 | 96,162,000 | -5,900,000 | $65.89 |
| 06/30/2022 | Blueprint Medicines Corp | BPMC | 2,020,629 | 99,282 | 102,062,000 | -20,674,000 | $50.51 |
| 03/31/2022 | Blueprint Medicines Corp | BPMC | 1,921,347 | 1,470,690 | 122,736,000 | 74,466,000 | $63.88 |
| 12/31/2021 | Blueprint Medicines Corp | BPMC | 450,657 | -601,546 | 48,270,000 | -59,907,000 | $107.11 |
| 09/30/2021 | Blueprint Medicines Corp | BPMC | 1,052,203 | -269,110 | 108,177,000 | -8,046,000 | $102.81 |
| 06/30/2021 | Blueprint Medicines Corp | BPMC | 1,321,313 | 407,611 | 116,223,000 | 27,384,000 | $87.96 |
| 03/31/2021 | Blueprint Medicines Corp | BPMC | 913,702 | -145,748 | 88,839,000 | -29,978,000 | $97.23 |
| 12/31/2020 | Blueprint Medicines Corp | BPMC | 1,059,450 | -1,627,406 | 118,817,000 | -130,255,000 | $112.15 |
| 09/30/2020 | Blueprint Medicines Corp | BPMC | 2,686,856 | 1,488,867 | 249,072,000 | 155,629,000 | $92.70 |
| 06/30/2020 | Blueprint Medicines Corp | BPMC | 1,197,989 | -28,107 | 93,443,000 | 21,741,000 | $78.00 |
| 03/31/2020 | Blueprint Medicines Corp | BPMC | 1,226,096 | -741,942 | 71,702,000 | -85,958,000 | $58.48 |
| 12/31/2019 | Blueprint Medicines Corp | BPMC | 1,968,038 | 549,334 | 157,660,000 | 53,428,000 | $80.11 |
| 09/30/2019 | Blueprint Medicines Corp | BPMC | 1,418,704 | 895,443 | 104,232,000 | 54,873,000 | $73.47 |
| 06/30/2019 | Blueprint Medicines Corp | BPMC | 523,261 | 323,261 | 49,359,000 | 33,349,000 | $94.33 |
| 03/31/2019 | Blueprint Medicines Corp | BPMC | 200,000 | 200,000 | 16,010,000 | 16,010,000 | $80.05 |
| 12/31/2017 | Blueprint Medicines Corp | BPMC | 0 | -313,965 | 0 | -21,874,000 | |
| 09/30/2017 | Blueprint Medicines Corp | BPMC | 313,965 | -143,137 | 21,874,000 | -1,287,000 | $69.67 |
| 06/30/2017 | Blueprint Medicines Corp | BPMC | 457,102 | 282,202 | 23,161,000 | 16,167,000 | $50.67 |
| 03/31/2017 | Blueprint Medicines Corp | BPMC | 174,900 | 174,900 | 6,994,000 | 6,994,000 | $39.99 |
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