| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 04/04/2023 | BOYNTON ALTON L | CHIEF SCIENTIFIC OFFICER | Gift | STOCK OPTIONS | 6.8M | $0.35 | $2.4M | | 04/04/2023 |
| 04/03/2023 | BOSCH MARNIX L | Chief Technical Officer | Grant | Common Stock | 119.4k | $0.25 | $29.8k | | 04/03/2023 |
| 12/01/2022 | JASINOWSKI JERRY J | Director | Grant | Series C Convertible Preferred Stock | 28.2k | $21.25 | $600k | | 12/01/2022 |
| 01/19/2021 | BOYNTON ALTON L | CHIEF SCIENTIFIC OFFICER | Gift | Employee Stock Option (Right to Buy) | 3.4M | $0.25 | $850.7k | | 01/19/2021 |
| 10/14/2020 | Powers Linda F | President and CEO | Gift | Options to purchase Common Stock | 3M | $0.25 | $750k | | 10/14/2020 |
| 07/02/2020 | Powers Linda F | President and CEO | Grant | Warrants to purchase Common Stock | 15.2M | $0.21 | $3.2M | | 07/02/2020 |
| 07/02/2020 | BOSCH MARNIX L | Chief Technical Officer | Grant | Options to purchase Common Stock, par value $0.001 | 16.6M | $0.25 | $4.2M | | 07/02/2020 |
| 07/02/2020 | Goldman Leslie J. | See Remarks | Grant | Options to purchase Common Stock, par value $0.001 | 21.8M | $0.25 | $5.5M | | 07/02/2020 |
| 07/02/2020 | Goldman Leslie J. | See Remarks | Grant | Options to purchase Common Stock, par value $0.001 | 1.3M | $0.25 | $328.9k | | 07/02/2020 |
| 07/02/2020 | Goldman Leslie J. | See Remarks | Grant | Options to purchase Common Stock, par value $0.001 | 5.4M | $0.21 | $1.1M | | 07/02/2020 |
| 07/02/2020 | Powers Linda F | President and CEO | Grant | Options to purchase Common Stock, par value $0.001 | 32.6M | $0.25 | $8.1M | | 07/02/2020 |
| 07/02/2020 | Powers Linda F | President and CEO | Grant | Options to purchase Common Stock, par value $0.001 | 2.1M | $0.25 | $526.2k | | 07/02/2020 |
| 07/02/2020 | Powers Linda F | President and CEO | Grant | Options to purchase Common Stock, par value $0.001 | 8.7M | $0.21 | $1.8M | | 07/02/2020 |
| 07/02/2020 | BOSCH MARNIX L | Chief Technical Officer | Grant | Options to purchase Common Stock, par value $0.001 | 7.5M | $0.25 | $1.9M | | 07/02/2020 |
| 07/02/2020 | BOSCH MARNIX L | Chief Technical Officer | Grant | Options to purchase Common Stock, par value $0.001 | 3.2M | $0.21 | $682.4k | | 07/02/2020 |
| 07/02/2020 | BOYNTON ALTON L | CHIEF SCIENTIFIC OFFICER | Grant | Options to purchase Common Stock, par value $0.001 | 605.2k | $0.25 | $151.3k | | 07/02/2020 |
| 07/02/2020 | BOYNTON ALTON L | CHIEF SCIENTIFIC OFFICER | Grant | Options to purchase Common Stock, par value $0.001 | 2.5M | $0.21 | $523.2k | | 07/02/2020 |
| 07/02/2020 | BOYNTON ALTON L | CHIEF SCIENTIFIC OFFICER | Grant | Options to purchase Common Stock, par value $0.001 | 15.7M | $0.25 | $3.9M | | 07/02/2020 |
| 04/30/2020 | Powers Linda F | President and CEO | Other (acquisition) | Warrants | 29.4M | $0.22 | $6.5M | | 04/30/2020 |
| 04/30/2020 | Powers Linda F | President and CEO | Other | Warrants | 29.4M | $0.22 | $6.5M | | 04/30/2020 |
| 02/03/2020 | JASINOWSKI JERRY J | Director | Grant | Common Stock | 526.3k | $0.19 | $100k | | 02/03/2020 |
| 12/28/2018 | Powers Linda F | President and CEO | Sale | Class D-2 Warrants | 402.1k | $0.30 | $120.6k | Sale by Toucan Capital Fund III, LP. | 12/27/2018 |
| 12/28/2018 | Powers Linda F | President and CEO | Sale | Restricted Common Stock, par value $0.001 | 804.1k | $0.17 | $136.7k | Sale by Toucan Capital Fund III, LP. | 12/27/2018 |
| 12/27/2018 | Powers Linda F | President and CEO | Sale | Restricted Common Stock, par value $0.001 | 3.6M | $0.17 | $605k | | 12/27/2018 |
| 12/27/2018 | Powers Linda F | President and CEO | Sale | Class D-2 Warrants | 1.8M | $0.30 | $533.8k | | 12/27/2018 |
| 05/28/2018 | Powers Linda F | President and CEO | Grant | Options to purchase Common Stock, par value $0.001 | 39.2M | $0.23 | $9M | | 05/28/2018 |
| 05/28/2018 | BLACK COFER | Director | Grant | Options to purchase Common Stock, par value $0.001 | 1.7M | $0.23 | $394.4k | | 05/28/2018 |
| 05/28/2018 | Goldman Leslie J. | See Remarks | Grant | Options to purchase Common Stock, par value $0.001 | 24.5M | $0.23 | $5.6M | | 05/28/2018 |
| 05/28/2018 | MALIK NAVID | Director | Grant | Options to purchase Common Stock, par value $0.001 | 9.1M | $0.23 | $2.1M | | 05/28/2018 |
| 05/28/2018 | JASINOWSKI JERRY J | Director | Grant | Options to purchase Common Stock, par value $0.001 | 4.9M | $0.23 | $1.1M | | 05/28/2018 |
| 05/28/2018 | BOYNTON ALTON L | CHIEF SCIENTIFIC OFFICER | Grant | Options to purchase Common Stock, par value $0.001 | 4.9M | $0.23 | $1.1M | | 05/28/2018 |
| 03/19/2018 | Powers Linda F | President and CEO | Grant | Convertible Note | 0 | $0.00 | $0 | | 03/19/2018 |
| 03/19/2018 | Powers Linda F | President and CEO | Grant | | 869.6k | $0.30 | $260.9k | | 03/19/2018 |
| 03/19/2018 | Powers Linda F | President and CEO | Grant | Convertible Note | 0 | $0.00 | $0 | | 03/19/2018 |
| 03/14/2018 | Powers Linda F | President and CEO | Grant | Convertible Note | 0 | $0.00 | $0 | | 03/12/2018 |
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