| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 10/02/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 4.8k | $16.07 | $76.7k | | 09/29/2023 |
| 10/02/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 902 | $16.07 | $14.5k | By Adjuvant Global Health Technology Fund DE, L.P. | 09/29/2023 |
| 10/02/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 4.8k | $16.07 | $76.7k | By Adjuvant Global Health Technology Fund, L.P. | 09/29/2023 |
| 10/02/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 902 | $16.07 | $14.5k | By Adjuvant Global Health Technology Fund DE, L.P. | 09/29/2023 |
| 09/29/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 15.8k | $16.28 | $256.6k | By Adjuvant Global Health Technology Fund DE, L.P. | 09/29/2023 |
| 09/29/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 83.3k | $16.28 | $1.4M | By Adjuvant Global Health Technology Fund, L.P. | 09/29/2023 |
| 09/29/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 83.3k | $16.28 | $1.4M | | 09/29/2023 |
| 09/29/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 15.8k | $16.28 | $256.6k | By Adjuvant Global Health Technology Fund DE, L.P. | 09/29/2023 |
| 09/28/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 7.2k | $16.11 | $115.3k | By Adjuvant Global Health Technology Fund, L.P.( | 09/27/2023 |
| 09/28/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 1.4k | $16.11 | $21.8k | By Adjuvant Global Health Technology Fund DE, L.P | 09/27/2023 |
| 09/28/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 7.2k | $16.11 | $115.3k | | 09/27/2023 |
| 09/28/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 1.4k | $16.11 | $21.8k | By Adjuvant Global Health Technology Fund DE, L.P | 09/27/2023 |
| 09/27/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 707 | $16.07 | $11.4k | | 09/27/2023 |
| 09/27/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 134 | $16.07 | $2.2k | By Adjuvant Global Health Technology Fund DE, L.P | 09/27/2023 |
| 09/27/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 707 | $16.07 | $11.4k | By Adjuvant Global Health Technology Fund, L.P. | 09/27/2023 |
| 09/27/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 134 | $16.07 | $2.2k | By Adjuvant Global Health Technology Fund DE, L.P. | 09/27/2023 |
| 08/23/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 64 | $16.00 | $1k | By Adjuvant Global Health Technology Fund DE, L.P. | 08/23/2023 |
| 08/23/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 336 | $16.00 | $5.4k | By Adjuvant Global Health Technology Fund, L.P. | 08/23/2023 |
| 08/23/2023 | Aziz Kabeer | 10% Owner | Sale | Common Stock | 64 | $16.00 | $1k | By Adjuvant Global Health Technology Fund DE, L.P. | 08/23/2023 |
| 08/23/2023 | Adjuvant Global Health Technology Fund, L.P. | 10% Owner | Sale | Common Stock | 336 | $16.00 | $5.4k | | 08/23/2023 |
| 08/18/2023 | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Purchase | Common Stock | 1.8M | $9.00 | $16M | See Footnotes | 08/18/2023 |
| 06/07/2023 | FitzPatrick Margaret M | Director | Grant | Stock Option (right to buy) | 23.7k | $5.91 | $140.3k | | 06/07/2023 |
| 06/07/2023 | Wong Stephanie | Director | Grant | Stock Option (right to buy) | 23.7k | $5.91 | $140.3k | | 06/07/2023 |
| 06/07/2023 | Spigelman Melvin K | Director | Grant | Stock Option (right to buy) | 23.7k | $5.91 | $140.3k | | 06/07/2023 |
| 06/07/2023 | Zakrzewski Joseph S | Director | Grant | Stock Option (right to buy) | 23.7k | $5.91 | $140.3k | | 06/07/2023 |
| 06/07/2023 | Readnour Robin Shane | Director | Grant | Stock Option (right to buy) | 23.7k | $5.91 | $140.3k | | 06/07/2023 |
| 06/07/2023 | Martin Patricia A. | Director | Grant | Stock Option (right to buy) | 23.7k | $5.91 | $140.3k | | 06/07/2023 |
| 06/07/2023 | Marks Gilbert Lynn | Director | Grant | Stock Option (right to buy) | 23.7k | $5.91 | $140.3k | | 06/07/2023 |
| 06/07/2023 | Aziz Kabeer | 10% Owner | Grant | Stock Option (right to buy) | 23.7k | $5.91 | $140.3k | | 06/07/2023 |
| 05/15/2023 | Easom Eric | CEO | Purchase | Common Stock | 10k | $5.38 | $53.8k | See Footnote | 05/15/2023 |
| 02/23/2023 | Easom Eric | CEO | Grant | Stock Option (right to buy) | 267.6k | $11.99 | $3.2M | | 02/23/2023 |
| 11/14/2022 | Easom Eric | CEO | Sale | Common Stock | 23 | $15.04 | $345.9 | | 11/10/2022 |
| 11/10/2022 | Easom Eric | CEO | Sale | Common Stock | 4.4k | $15.32 | $67.6k | | 11/10/2022 |
| 11/07/2022 | Easom Eric | CEO | Sale | Common Stock | 10.2k | $15.90 | $161.7k | | 11/03/2022 |
| 11/07/2022 | Easom Eric | CEO | Sale | Common Stock | 2k | $16.72 | $34k | | 11/03/2022 |
|