| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 07/24/2023 | KODIAK VENTURE PARTNERS III LP | | Other (disposition) | Common Stock, par value $0.0001 per share | 9.8M | $0.00 | $0 | | 07/24/2023 |
| 07/24/2023 | Clarke Dennis A. | | Other (acquisition) | Common Stock, par value $0.0001 per share | 25.5k | $0.00 | $2.6 | | 07/24/2023 |
| 07/24/2023 | Anderson Eric Senior | | Other (disposition) | Common Stock, par value $0.0001 per share | 25.5k | $0.00 | $2.6 | | 07/24/2023 |
| 07/24/2023 | Cummings Foundation, Inc. | | Other (disposition) | Common Stock, par value $0.0001 per share | 1.3M | $0.00 | $127.6 | | 07/24/2023 |
| 08/11/2022 | Morningside Venture Investments Ltd | 10% Owner | Purchase | Common Stock | 3.1M | $3.92 | $12M | | 08/11/2022 |
| 08/11/2022 | Walker Matthew Alan | 10% Owner | Purchase | Common Stock | 6.4M | $3.92 | $25M | by Builders Vision, LLC | 08/11/2022 |
| 08/11/2022 | Walker Matthew Alan | 10% Owner | Purchase | Common Stock | 63.8k | $3.92 | $250k | | 08/11/2022 |
| 08/11/2022 | Builders Vision, LLC | 10% Owner | Purchase | Common Stock | 127.6k | $3.92 | $500k | by Builders Vision, LLC | 08/11/2022 |
| 08/11/2022 | Builders Vision, LLC | 10% Owner | Purchase | Common Stock | 6.4M | $3.92 | $25M | by Builders Vision, LLC | 08/11/2022 |
| 06/01/2022 | Ortega-Valle Marta | Chief Business Officer | Exercise | Stock Option (Right to Buy) | 29.8k | $0.23 | $6.9k | | 06/01/2022 |
| 05/10/2022 | COONEY CHARLES L | Director | Grant | Stock Option (Right to Buy) | 95k | $7.96 | $756.2k | | 05/10/2022 |
| 05/10/2022 | COBB CAROLE B | COO | Grant | Stock Option (Right to Buy) | 180k | $7.96 | $1.4M | | 05/10/2022 |
| 05/10/2022 | Kennedy David | General Counsel | Grant | Stock Option (Right to Buy) | 318.8k | $7.96 | $2.5M | | 05/10/2022 |
| 05/10/2022 | Keefe Susan | CFO & Interim CAO | Grant | Stock Option (Right to Buy) | 180k | $7.96 | $1.4M | | 05/10/2022 |
| 05/10/2022 | Khan Amin | Chief Scientific Officer | Grant | Stock Option (Right to Buy) | 318.8k | $7.96 | $2.5M | | 05/10/2022 |
| 05/10/2022 | Singleton Mark | Sr. VP of Technology | Grant | Stock Option (Right to Buy) | 471.2k | $7.96 | $3.8M | | 05/10/2022 |
| 05/10/2022 | Ortega-Valle Marta | Chief Business Officer | Grant | Stock Option (Right to Buy) | 180k | $7.96 | $1.4M | | 05/10/2022 |
| 05/10/2022 | Manocha Charu | Chief People Officer | Grant | Stock Option (Right to Buy) | 253.4k | $7.96 | $2M | | 05/10/2022 |
| 05/10/2022 | Walker Matthew Alan | 10% Owner | Grant | Stock Option (Right to Buy) | 65k | $7.96 | $517.4k | | 05/10/2022 |
| 05/10/2022 | Schlicher Martha | Director | Grant | Stock Option (Right to Buy) | 65k | $7.96 | $517.4k | | 05/10/2022 |
| 05/10/2022 | OBrien Eric | Director | Grant | Stock Option (Right to Buy) | 65k | $7.96 | $517.4k | | 05/10/2022 |
| 05/10/2022 | KISHORE GANESH | Director | Grant | Stock Option (Right to Buy) | 65k | $7.96 | $517.4k | | 05/10/2022 |
| 05/10/2022 | Pardi Jennifer E | Director | Grant | Stock Option (Right to Buy) | 65k | $7.96 | $517.4k | | 05/10/2022 |
| 02/02/2022 | COONEY CHARLES L | Director | Grant | Common Stock | 305.3k | $0.00 | $0 | | 02/02/2022 |
| 02/02/2022 | Morningside Venture Investments Ltd | 10% Owner | Conversion | Common Stock | 12.9M | $0.00 | $0 | | 02/02/2022 |
| 02/02/2022 | Morningside Venture Investments Ltd | 10% Owner | Purchase | Common Stock | 1000k | $0.00 | $0 | | 02/02/2022 |
| 02/02/2022 | Morningside Venture Investments Ltd | 10% Owner | Conversion | Class A Common Stock | 12.9M | $0.00 | $0 | | 02/02/2022 |
| 02/02/2022 | Morningside Venture Investments Ltd | 10% Owner | Conversion | Class A Common Stock | 1000k | $10.00 | $10M | | 02/02/2022 |
| 02/02/2022 | Keefe Susan | CFO & Interim CAO | Grant | Stock Option (Right to Buy) | 488.5k | $0.50 | $244.2k | | 02/02/2022 |
| 02/02/2022 | Keefe Susan | CFO & Interim CAO | Grant | Stock Option (Right to Buy) | 565.8k | $0.98 | $554.4k | | 02/02/2022 |
| 02/02/2022 | COBB CAROLE B | COO | Grant | Stock Option (Right to Buy) | 427.8k | $0.35 | $149.7k | | 02/02/2022 |
| 02/02/2022 | COBB CAROLE B | COO | Grant | Stock Option (Right to Buy) | 43.9k | $0.35 | $15.4k | | 02/02/2022 |
| 02/02/2022 | COBB CAROLE B | COO | Grant | Stock Option (Right to Buy) | 459.3k | $0.33 | $151.6k | | 02/02/2022 |
| 02/02/2022 | COBB CAROLE B | COO | Grant | Stock Option (Right to Buy) | 187.8k | $0.33 | $62k | | 02/02/2022 |
| 02/02/2022 | COBB CAROLE B | COO | Grant | Stock Option (Right to Buy) | 480.6k | $0.50 | $240.3k | | 02/02/2022 |
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