| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 12.9k | $108.76 | $1.4M | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 34.1k | $110.20 | $3.8M | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 86.6k | $29.56 | $2.6M | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 102.2k | $36.32 | $3.7M | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 135.9k | $6.70 | $910.6k | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 93k | $3.70 | $344.2k | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 52.8k | $3.10 | $163.8k | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Common Stock | 88k | $0.00 | $0 | | 06/16/2023 |
| 06/02/2023 | Prometheus Biosciences, Inc. | RXDX | Exercise | Stock Options (Right to Buy) | 78.2k | $3.10 | $242.3k | | 06/02/2023 |
| 03/06/2023 | Prometheus Biosciences, Inc. | RXDX | Sale | Common Stock | 10k | $122.13 | $1.2M | | 03/06/2023 |
| 03/06/2023 | Prometheus Biosciences, Inc. | RXDX | Exercise | Stock Option (Right to Buy) | 10k | $3.70 | $37k | | 03/06/2023 |
| 01/17/2023 | Prometheus Biosciences, Inc. | RXDX | Sale | Common Stock | 5k | $119.00 | $595k | | 01/17/2023 |
| 01/17/2023 | Prometheus Biosciences, Inc. | RXDX | Exercise | Stock Option (Right to Buy) | 5k | $3.70 | $18.5k | | 01/17/2023 |
| 12/16/2022 | Prometheus Biosciences, Inc. | RXDX | Grant | Stock Option (Right to Buy) | 12.9k | $108.76 | $1.4M | | 12/16/2022 |
| 12/09/2022 | Prometheus Biosciences, Inc. | RXDX | Grant | Common Stock | 9.8k | $0.00 | $0 | | 12/09/2022 |
| 12/09/2022 | Prometheus Biosciences, Inc. | RXDX | Grant | Stock Option (Right to Buy) | 34.1k | $110.20 | $3.8M | | 12/09/2022 |
| 05/20/2022 | Prometheus Biosciences, Inc. | RXDX | Grant | Stock Option (Right to Buy) | 86.6k | $29.56 | $2.6M | | 05/20/2022 |
| 11/14/2021 | Prometheus Biosciences, Inc. | RXDX | Grant | Stock Option (Right to Buy) | 102.2k | $36.32 | $3.7M | | 11/14/2021 |
| 05/22/2020 | Histogen Inc. | CNAT | Exercise | Restricted Stock Units | 38.5k | $0.00 | $0 | | 05/22/2020 |
| 05/22/2020 | Histogen Inc. | CNAT | Payment of Exercise | Common Stock | 18.6k | $0.56 | $10.4k | | 05/22/2020 |
| 02/07/2019 | Histogen Inc. | CNAT | Grant | Stock Option (Right to Buy) | 175k | $2.00 | $350k | | 02/07/2019 |
| 02/04/2018 | Histogen Inc. | CNAT | Grant | Stock Option (Right to Buy) | 70k | $5.17 | $361.9k | | 02/04/2018 |
| 08/31/2017 | Histogen Inc. | CNAT | Grant | Stock Option (Right to Buy) | 525k | $5.74 | $3M | | 08/31/2017 |