| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 11/16/2022 | Protagonist Therapeutics, Inc | PTGX | Exercise | Stock Option (right to buy) | 35.3k | $4.21 | $148.7k | | 11/16/2022 |
| 11/16/2022 | Protagonist Therapeutics, Inc | PTGX | Exercise | Stock Option (right to buy) | 35.7k | $1.16 | $41.4k | | 11/16/2022 |
| 11/16/2022 | Protagonist Therapeutics, Inc | PTGX | Exercise | Stock Option (right to buy) | 6k | $1.89 | $11.3k | | 11/16/2022 |
| 11/16/2022 | Protagonist Therapeutics, Inc | PTGX | Exercise | Stock Option (right to buy) | 9.7k | $1.89 | $18.4k | | 11/16/2022 |
| 11/16/2022 | Protagonist Therapeutics, Inc | PTGX | Exercise | Stock Option (right to buy) | 13.8k | $0.87 | $12k | | 11/16/2022 |
| 02/28/2022 | Protagonist Therapeutics, Inc | PTGX | Payment of Exercise | Common Stock | 2.1k | $24.28 | $51.4k | | 02/28/2022 |
| 02/15/2022 | Protagonist Therapeutics, Inc | PTGX | Grant | Common Stock | 10k | $0.00 | $0 | | 02/15/2022 |
| 02/15/2022 | Protagonist Therapeutics, Inc | PTGX | Grant | Stock Option (right to buy) | 60k | $28.73 | $1.7M | | 02/15/2022 |
| 02/26/2021 | Protagonist Therapeutics, Inc | PTGX | Grant | Stock Option (right to buy) | 65k | $23.57 | $1.5M | | 02/26/2021 |
| 02/26/2021 | Protagonist Therapeutics, Inc | PTGX | Grant | Common Stock | 10k | $0.00 | $0 | | 02/26/2021 |
| 02/28/2020 | Protagonist Therapeutics, Inc | PTGX | Grant | Stock Option (right to buy) | 70k | $7.80 | $546k | | 02/28/2020 |
| 08/06/2019 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 3.4k | $8.85 | $30k | | 08/06/2019 |
| 03/01/2019 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 810 | $8.03 | $6.5k | | 02/28/2019 |
| 02/28/2019 | Protagonist Therapeutics, Inc | PTGX | Grant | Employee Stock Option (right to buy) | 90k | $8.02 | $721.8k | | 02/28/2019 |
| 02/28/2019 | Protagonist Therapeutics, Inc | PTGX | Grant | Common Stock | 15k | $0.00 | $0 | | 02/28/2019 |
| 02/06/2019 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 3.8k | $7.74 | $29.6k | | 02/06/2019 |
| 08/15/2018 | Protagonist Therapeutics, Inc | PTGX | Grant | Common Stock | 25.8k | $0.00 | $0 | | 08/15/2018 |
| 08/15/2018 | Protagonist Therapeutics, Inc | PTGX | Grant | Stock Option (right to buy) | 17.2k | $8.58 | $147.6k | | 08/15/2018 |
| 03/12/2018 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 3.5k | $21.29 | $74.5k | | 03/12/2018 |
| 03/12/2018 | Protagonist Therapeutics, Inc | PTGX | Exercise | Employee Stock Option (right to buy) | 3.5k | $4.21 | $14.7k | | 03/12/2018 |
| 03/02/2018 | Protagonist Therapeutics, Inc | PTGX | Exercise | Employee Stock Option (right to buy) | 875 | $1.89 | $1.7k | | 02/28/2018 |
| 03/02/2018 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 875 | $20.00 | $17.5k | | 02/28/2018 |
| 02/28/2018 | Protagonist Therapeutics, Inc | PTGX | Grant | Common Stock | 9.5k | $0.00 | $0 | | 02/28/2018 |
| 02/28/2018 | Protagonist Therapeutics, Inc | PTGX | Grant | Employee Stock Option (right to buy) | 56.5k | $16.95 | $957.7k | | 02/28/2018 |
| 01/16/2018 | Protagonist Therapeutics, Inc | PTGX | Exercise | Employee Stock Option (right to buy) | 875 | $1.89 | $1.7k | | 01/16/2018 |
| 01/16/2018 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 875 | $20.00 | $17.5k | | 01/16/2018 |
| 12/18/2017 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 875 | $20.00 | $17.5k | | 12/18/2017 |
| 12/18/2017 | Protagonist Therapeutics, Inc | PTGX | Exercise | Employee Stock Option (right to buy) | 875 | $1.89 | $1.7k | | 12/18/2017 |
| 11/30/2017 | Protagonist Therapeutics, Inc | PTGX | Grant | Common Stock | 875 | $1.89 | $1.7k | | 11/30/2017 |
| 11/30/2017 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 875 | $20.00 | $17.5k | | 11/30/2017 |
| 11/30/2017 | Protagonist Therapeutics, Inc | PTGX | Exercise | Employee Stock Option (right to buy) | 875 | $1.89 | $1.7k | | 11/30/2017 |
| 11/13/2017 | Protagonist Therapeutics, Inc | PTGX | Sale | Common Stock | 3.5k | $16.97 | $59.4k | | 11/13/2017 |
| 11/13/2017 | Protagonist Therapeutics, Inc | PTGX | Exercise | Employee Stock Option (right to buy) | 3.5k | $4.21 | $14.7k | | 11/13/2017 |
| 11/13/2017 | Protagonist Therapeutics, Inc | PTGX | Exercise | Employee Stock Option (right to buy) | 3.5k | $1.89 | $6.6k | | 11/13/2017 |