| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/09/2023 | Disc Medicine, Inc. | | Grant | Stock Option (Right to Buy) | 7.1k | $45.69 | $326k | | 06/09/2023 |
| 02/23/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 6.3k | $38.60 | $242.9k | | 02/23/2023 |
| 02/23/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/23/2023 |
| 02/22/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Common Stock | 3.9k | $0.00 | $0 | | 02/22/2023 |
| 02/22/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Disposition | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/22/2023 |
| 12/29/2022 | Disc Medicine, Inc. | | Grant | Stock Option (Right to Buy) | 7k | $13.50 | $94.5k | | 12/29/2022 |
| 02/22/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 6.8k | $32.20 | $220.5k | | 02/22/2022 |
| 02/22/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/22/2022 |
| 02/19/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Common Stock | 4.2k | $0.00 | $0 | | 02/19/2022 |
| 02/19/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Disposition | Restricted Stock Units | 4.2k | $0.00 | $0 | | 02/19/2022 |
| 01/03/2022 | Disc Medicine, Inc. | | Grant | Stock Option (Right to Buy) | 793.3k | $3.08 | $2.4M | | 01/03/2022 |
| 11/15/2021 | Disc Medicine, Inc. | | Grant | Stock Option (Right to Buy) | 17.2k | $3.58 | $61.7k | | 11/15/2021 |
| 11/15/2021 | Disc Medicine, Inc. | | Grant | Stock Option (Right to Buy) | 23.5k | $3.58 | $84.2k | | 11/15/2021 |
| 04/29/2021 | Disc Medicine, Inc. | | Grant | Stock Option (Right to Buy) | 45.5k | $11.92 | $542k | | 04/29/2021 |
| 02/19/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 7.4k | $29.61 | $218.1k | | 02/19/2021 |
| 02/19/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Restricted Stock Units | 4.2k | $0.00 | $0 | | 02/19/2021 |
| 08/05/2020 | MOMENTA PHARMACEUTICALS INC | MNTA | Sale | Common Stock | 10k | $33.00 | $330k | | 08/05/2020 |
| 08/05/2020 | MOMENTA PHARMACEUTICALS INC | MNTA | Exercise | Stock Option (Right to Buy) | 10k | $14.84 | $148.4k | | 08/05/2020 |
| 07/29/2020 | MOMENTA PHARMACEUTICALS INC | MNTA | Sale | Common Stock | 10k | $30.00 | $300k | | 07/29/2020 |
| 07/29/2020 | MOMENTA PHARMACEUTICALS INC | MNTA | Exercise | Stock Option (Right to Buy) | 10k | $14.84 | $148.4k | | 07/29/2020 |
| 06/23/2020 | MOMENTA PHARMACEUTICALS INC | MNTA | Grant | Stock Option (Right to Buy) | 25k | $38.09 | $952.2k | | 06/23/2020 |
| 02/21/2020 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Common Stock | 5.2k | $23.99 | $125k | | 02/21/2020 |
| 02/21/2020 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 9.3k | $23.99 | $223.2k | | 02/21/2020 |
| 06/20/2019 | MOMENTA PHARMACEUTICALS INC | MNTA | Exercise | Restricted Stock Unit | 4.4k | $0.00 | $0 | | 06/19/2019 |
| 06/19/2019 | MOMENTA PHARMACEUTICALS INC | MNTA | Grant | Stock Option (Right to Buy) | 25k | $12.64 | $316k | | 06/19/2019 |
| 02/22/2019 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 12.4k | $36.75 | $456.7k | | 02/22/2019 |
| 06/20/2018 | MOMENTA PHARMACEUTICALS INC | MNTA | Exercise | Restricted Stock Units | 5.7k | $0.00 | $0 | | 06/20/2018 |
| 06/20/2018 | MOMENTA PHARMACEUTICALS INC | MNTA | Grant | Restricted Stock Units | 4.4k | $0.00 | $0 | | 06/20/2018 |
| 06/20/2018 | MOMENTA PHARMACEUTICALS INC | MNTA | Grant | Stock Option (Right to Buy) | 8.9k | $22.30 | $197.5k | | 06/20/2018 |
| 02/23/2018 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 8.6k | $39.40 | $339.4k | | 02/23/2018 |
| 11/07/2017 | Dimension Therapeutics, Inc. | DMTX | Disposition | Stock Option (Right to Buy) | 44.5k | $4.85 | $215.7k | | 11/07/2017 |
| 11/07/2017 | Dimension Therapeutics, Inc. | DMTX | Disposition | Stock Option (Right to Buy) | 32.1k | $7.08 | $227k | | 11/07/2017 |
| 11/07/2017 | Dimension Therapeutics, Inc. | DMTX | Disposition | Stock Option (Right to Buy) | 17k | $1.15 | $19.6k | | 11/07/2017 |
| 06/13/2017 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 6k | $38.60 | $233k | | 06/13/2017 |
| 05/25/2017 | Dimension Therapeutics, Inc. | DMTX | Grant | Stock Option (Right to Buy) | 17k | $1.15 | $19.6k | | 05/25/2017 |
|