| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/20/2023 | Avidity Biosciences, Inc. | RNA | Grant | Common Stock | 50k | $0.00 | $0 | | 01/20/2023 |
| 01/20/2023 | Avidity Biosciences, Inc. | RNA | Grant | Stock Option (Right to Buy) | 400k | $22.47 | $9M | | 01/20/2023 |
| 11/10/2022 | OmniAb, Inc. | | Purchase | Common Stock | 15k | $2.92 | $43.8k | By spouse | 11/09/2022 |
| 11/09/2022 | OmniAb, Inc. | | Purchase | Common Stock | 21k | $2.74 | $57.6k | By spouse | 11/09/2022 |
| 08/25/2022 | Avidity Biosciences, Inc. | RNA | Sale | Common Stock | 14.9k | $23.07 | $342.7k | | 08/24/2022 |
| 08/25/2022 | Avidity Biosciences, Inc. | RNA | Exercise | Stock Option (Right to Buy) | 14.9k | $1.24 | $18.4k | | 08/24/2022 |
| 08/24/2022 | Avidity Biosciences, Inc. | RNA | Exercise | Stock Option (Right to Buy) | 35k | $1.24 | $43.5k | | 08/24/2022 |
| 08/24/2022 | Avidity Biosciences, Inc. | RNA | Sale | Common Stock | 35k | $22.80 | $798.9k | | 08/24/2022 |
| 08/15/2022 | Avidity Biosciences, Inc. | RNA | Sale | Common Stock | 100 | $22.47 | $2.2k | | 08/15/2022 |
| 08/15/2022 | Avidity Biosciences, Inc. | RNA | Exercise | Stock Option (Right to Buy) | 100 | $1.24 | $124 | | 08/15/2022 |
| 06/10/2022 | LIGAND PHARMACEUTICALS INC | LGND | Grant | Common Stock | 1k | $0.00 | $0 | | 06/10/2022 |
| 06/10/2022 | LIGAND PHARMACEUTICALS INC | LGND | Grant | Non-Qualified Stock Option (right to buy) | 4.3k | $79.29 | $344.1k | | 06/10/2022 |
| 01/21/2022 | Avidity Biosciences, Inc. | RNA | Grant | Stock Option (Right to Buy) | 425k | $14.22 | $6M | | 01/21/2022 |
| 06/04/2021 | LIGAND PHARMACEUTICALS INC | LGND | Grant | Non-Qualified Stock Option (right to buy) | 3.3k | $115.39 | $377.2k | | 06/04/2021 |
| 06/04/2021 | LIGAND PHARMACEUTICALS INC | LGND | Grant | Common Stock | 630 | $0.00 | $0 | | 06/04/2021 |
| 05/14/2021 | PhenomeX Inc. | BLI | Grant | Common Stock | 1.4k | $0.00 | $0 | | 05/14/2021 |
| 05/14/2021 | PhenomeX Inc. | BLI | Grant | Stock Option (Right to Buy) | 4.9k | $37.13 | $181.9k | | 05/14/2021 |
| 03/01/2021 | PhenomeX Inc. | BLI | Sale | Common Stock | 3.2k | $62.37 | $201.3k | | 03/01/2021 |
| 03/01/2021 | PhenomeX Inc. | BLI | Exercise | Stock Option | 10k | $8.90 | $89k | | 03/01/2021 |
| 03/01/2021 | PhenomeX Inc. | BLI | Sale | Common Stock | 3k | $61.13 | $183.4k | | 03/01/2021 |
| 03/01/2021 | PhenomeX Inc. | BLI | Sale | Common Stock | 3.8k | $60.08 | $226.7k | | 03/01/2021 |
| 02/02/2021 | Avidity Biosciences, Inc. | RNA | Grant | Stock Option (Right to Buy) | 300k | $22.34 | $6.7M | | 02/02/2021 |
| 06/10/2020 | LIGAND PHARMACEUTICALS INC | LGND | Grant | Common Stock | 831 | $0.00 | $0 | | 06/10/2020 |
| 06/10/2020 | LIGAND PHARMACEUTICALS INC | LGND | Grant | Non-Qualified Stock Option (right to buy) | 2.5k | $117.58 | $290.2k | | 06/10/2020 |
| 10/15/2019 | LIGAND PHARMACEUTICALS INC | LGND | Grant | Non-Qualified Stock Option (right to buy) | 5.3k | $107.81 | $569.6k | | 10/15/2019 |
| 10/15/2019 | LIGAND PHARMACEUTICALS INC | LGND | Grant | Common Stock | 1.4k | $0.00 | $0 | | 10/15/2019 |
| 07/15/2019 | AKCEA THERAPEUTICS, INC. | AKCA | Sale | Common Stock | 1.8k | $23.52 | $42.8k | | 07/15/2019 |
| 07/01/2019 | AKCEA THERAPEUTICS, INC. | AKCA | Grant | Common Stock | 813 | $20.04 | $16.3k | | 07/01/2019 |
| 01/02/2019 | AKCEA THERAPEUTICS, INC. | AKCA | Grant | Stock Option (right to buy) | 173k | $30.73 | $5.3M | | 01/02/2019 |
| 04/17/2018 | AKCEA THERAPEUTICS, INC. | AKCA | Grant | Common Stock | 20.9k | $0.00 | $0 | | 04/17/2018 |
| 04/17/2018 | AKCEA THERAPEUTICS, INC. | AKCA | Grant | Stock Option (right to buy) | 1000k | $23.93 | $23.9M | | 04/17/2018 |
| 01/16/2018 | IONIS PHARMACEUTICALS INC | IONS | Sale | Common Stock | 2.2k | $51.76 | $113.7k | | 01/15/2018 |
| 01/15/2018 | IONIS PHARMACEUTICALS INC | IONS | Grant | Restricted Stock Units | 12.9k | $0.00 | $0 | | 01/15/2018 |
| 01/15/2018 | IONIS PHARMACEUTICALS INC | IONS | Exercise | Restricted Stock Units | 5.4k | $0.00 | $0 | | 01/15/2018 |
| 01/02/2018 | IONIS PHARMACEUTICALS INC | IONS | Grant | Employee Stock Option (right to buy) | 58.1k | $49.25 | $2.9M | | 01/01/2018 |
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