| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/14/2023 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 18.5k | $0.00 | $0 | | 08/14/2023 |
| 08/14/2023 | Adicet Bio, Inc. | TORC | Disposition | Stock Option (Right to Buy) | 18.5k | $11.49 | $212.6k | | 08/14/2023 |
| 08/14/2023 | Adicet Bio, Inc. | TORC | Disposition | Stock Option (Right to Buy) | 26.4k | $5.20 | $137.1k | | 08/14/2023 |
| 08/14/2023 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 26.4k | $0.00 | $0 | | 08/14/2023 |
| 08/14/2023 | Adicet Bio, Inc. | TORC | Disposition | Stock Option (Right to Buy) | 30k | $16.11 | $483.3k | | 08/14/2023 |
| 08/14/2023 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 30k | $0.00 | $0 | | 08/14/2023 |
| 08/14/2023 | Adicet Bio, Inc. | TORC | Disposition | Stock Option (Right to Buy) | 18.5k | $15.93 | $294.7k | | 08/14/2023 |
| 06/15/2023 | Schrodinger, Inc. | SDGR | Grant | | 6.2k | $0.00 | $0 | | 06/15/2023 |
| 06/15/2023 | Schrodinger, Inc. | SDGR | Grant | Stock Option (right to buy) | 12.5k | $45.26 | $565.8k | | 06/15/2023 |
| 06/01/2023 | Adicet Bio, Inc. | TORC | Grant | Common Stock | 5.9k | $0.00 | $0 | | 06/01/2023 |
| 06/01/2023 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 26.4k | $5.20 | $137.1k | | 06/01/2023 |
| 06/15/2022 | Schrodinger, Inc. | SDGR | Grant | Stock Option (right to buy) | 14.9k | $24.51 | $365.4k | | 06/15/2022 |
| 06/02/2022 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 18.5k | $11.49 | $212.6k | | 06/02/2022 |
| 05/26/2022 | Praxis Precision Medicines, Inc. | PRAX | Grant | Stock Option (Right to Buy) | 22.8k | $8.38 | $190.7k | | 05/26/2022 |
| 06/17/2021 | Schrodinger, Inc. | SDGR | Grant | Stock Option (right to buy) | 8.7k | $76.08 | $664.6k | | 06/17/2021 |
| 04/30/2021 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 18.5k | $15.93 | $294.7k | | 04/30/2021 |
| 04/13/2021 | Praxis Precision Medicines, Inc. | PRAX | Grant | Stock Option (Right to Buy) | 38.6k | $30.37 | $1.2M | | 04/13/2021 |
| 09/17/2020 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 30k | $16.11 | $483.3k | | 09/17/2020 |
| 06/03/2020 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 14.4k | $2.23 | $32.1k | | 06/03/2020 |
| 04/30/2020 | Schrodinger, Inc. | SDGR | Grant | Stock Option (right to buy) | 25.2k | $46.40 | $1.2M | | 04/30/2020 |
| 06/10/2019 | TETRAPHASE PHARMACEUTICALS INC | TTPH | Grant | Stock option (right to buy) | 16.5k | $0.77 | $12.7k | | 06/10/2019 |
| 05/08/2019 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 14.4k | $7.99 | $115.2k | | 05/08/2019 |
| 08/14/2018 | Adicet Bio, Inc. | TORC | Grant | Stock Option (Right to Buy) | 28.8k | $10.42 | $300.4k | | 08/14/2018 |
| 05/30/2018 | TETRAPHASE PHARMACEUTICALS INC | TTPH | Grant | Stock option (right to buy) | 12.5k | $3.68 | $46k | | 05/30/2018 |
| 02/12/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Sale | Common Stock | 1.3k | $149.21 | $194k | | 02/12/2018 |
| 02/12/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Sale | Common Stock | 1.1k | $150.47 | $165.5k | | 02/12/2018 |
| 02/12/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Sale | Common Stock | 2k | $151.26 | $305.8k | | 02/12/2018 |
| 02/12/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Sale | Common Stock | 400 | $152.62 | $61k | | 02/12/2018 |
| 02/12/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Sale | Common Stock | 300 | $153.69 | $46.1k | | 02/12/2018 |
| 02/06/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Grant | Common Stock | 12.1k | $0.00 | $0 | | 02/06/2018 |
| 02/06/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Grant | Common Stock | 10.1k | $0.00 | $0 | | 02/06/2018 |
| 02/06/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Grant | Stock Option (Right to Buy) | 23.5k | $155.57 | $3.7M | | 02/06/2018 |
| 02/05/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Sale | Common Stock | 700 | $159.62 | $111.7k | | 02/05/2018 |
| 02/05/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Sale | Common Stock | 500 | $160.50 | $80.2k | | 02/05/2018 |
| 02/05/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | Sale | Common Stock | 500 | $161.51 | $80.8k | | 02/05/2018 |
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