| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/12/2022 | GOLDFISCHER CARL | Director | Disposition | Common Stock, par value $0.0001 | 13.1k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | GOLDFISCHER CARL | Director | Disposition | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | GOLDFISCHER CARL | Director | Disposition | Common Stock, par value $0.0001 | 3.4M | $0.00 | $0 | See Footnote | 08/12/2022 |
| 08/12/2022 | Conroy Kevin T | Director | Disposition | Common Stock, par value $0.0001 | 53.3k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Conroy Kevin T | Director | Disposition | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | BATE KENNETH | Director | Disposition | Common Stock, par value $0.0001 | 8.1k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | BATE KENNETH | Director | Disposition | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | MOTT DAVID M | Director | Other | Common Stock, par value $0.0001 | 215.5k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | MOTT DAVID M | Director | Disposition | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | MOTT DAVID M | Director | Other | Common Stock, par value $0.0001 | 107k | $0.00 | $0 | See Note | 08/12/2022 |
| 08/12/2022 | BEVERIDGE, ROY A | Director | Disposition | Common Stock, par value $0.0001 | 20.3k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | BEVERIDGE, ROY A | Director | Disposition | Common Stock, par value $0.0001 | 25.7k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Kutok Jeffery | Chief Scientific Officer | Disposition | Common Stock, par value $0.0001 | 39k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Kutok Jeffery | Chief Scientific Officer | Disposition | Common Stock, par value $0.0001 | 81k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Bogle Grant C. | President and CEO | Disposition | Common Stock, par value $0.0001 | 84.2k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Bogle Grant C. | President and CEO | Disposition | Common Stock, par value $0.0001 | 175k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Giordano Michael F | Director | Disposition | Common Stock, par value $0.0001 | 8.1k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Giordano Michael F | Director | Disposition | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Agarwal Shefali | | Disposition | Common Stock, par value $0.0001 | 179.2k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Agarwal Shefali | | Disposition | Common Stock, par value $0.0001 | 107.3k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Beaulieu Joseph | See Remarks | Disposition | Common Stock, par value $0.0001 | 30.2k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Beaulieu Joseph | See Remarks | Disposition | Common Stock, par value $0.0001 | 21.9k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Richon Victoria | Director | Disposition | Common Stock, par value $0.0001 | 13.6k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Richon Victoria | Director | Disposition | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Legorreta Pablo G. | 10% Owner | Other | Common Stock, par value $0.0001 | 31.9M | $0.00 | $0 | See footnotes | 08/12/2022 |
| 08/12/2022 | Legorreta Pablo G. | 10% Owner | Disposition | Restricted Stock Units | 8.1k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Legorreta Pablo G. | 10% Owner | Disposition | Restricted Stock Units | 9k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Stuckley Carol | Director | Disposition | Common Stock, par value $0.0001 | 25.7k | $0.00 | $0 | | 08/12/2022 |
| 06/30/2022 | BEVERIDGE, ROY A | Director | Grant | Common Stock, par value $0.0001 | 8.9k | $1.47 | $13.1k | | 06/30/2022 |
| 06/30/2022 | MOTT DAVID M | Director | Grant | Common Stock, par value $0.0001 | 16.2k | $1.47 | $23.7k | | 06/30/2022 |
| 06/30/2022 | Conroy Kevin T | Director | Grant | Common Stock, par value $0.0001 | 10.2k | $1.47 | $15k | | 06/30/2022 |
| 05/17/2022 | BATE KENNETH | Director | Grant | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 05/17/2022 |
| 05/17/2022 | BATE KENNETH | Director | Grant | Stock Option (Right to Buy) | 41k | $0.56 | $23k | | 05/17/2022 |
| 05/17/2022 | Conroy Kevin T | Director | Grant | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 05/17/2022 |
| 05/17/2022 | Conroy Kevin T | Director | Grant | Stock Option (Right to Buy) | 41k | $0.56 | $23k | | 05/17/2022 |
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