| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/20/2023 | Koconis John | CEO & Chairman | Grant | Common Stock, par value $0.001 per share | 70.4k | $0.00 | $0 | | 08/20/2023 |
| 08/20/2023 | Lucchese Joseph | EVP & CFO | Grant | Common Stock, par value $0.001 | 35.2k | $0.00 | $0 | | 08/20/2023 |
| 08/20/2023 | Mendelsohn Alan | EVP & CMO | Grant | Common Stock, par value $0.001 per share | 35.2k | $0.00 | $0 | | 08/20/2023 |
| 12/15/2022 | Sitar Edward J | Director | Grant | Common Stock, par value $0.001 per share | 2.5k | $1.63 | $4.1k | | 12/15/2022 |
| 04/15/2022 | Sitar Edward J | Director | Grant | Common Stock, par value $0.001 per share | 150k | $0.00 | $0 | | 04/15/2022 |
| 04/15/2022 | Sitar Edward J | Director | Grant | Stock Option (right to buy) | 150k | $0.31 | $46k | | 04/15/2022 |
| 04/15/2022 | Cohen David E | Director | Grant | Common Stock, par value $0.001 per share | 100k | $0.00 | $0 | | 04/15/2022 |
| 04/15/2022 | Cohen David E | Director | Grant | Stock Option (right to buy) | 100k | $0.31 | $30.7k | | 04/15/2022 |
| 04/15/2022 | Lucchese Joseph | EVP & CFO | Grant | Stock Option (right to buy) | 300k | $0.31 | $92.1k | | 04/15/2022 |
| 04/15/2022 | Gaal Lubor | Director | Grant | Common Stock, par value $0.001 per share | 100k | $0.00 | $0 | | 04/15/2022 |
| 04/15/2022 | Gaal Lubor | Director | Grant | Stock Option (right to buy) | 100k | $0.31 | $30.7k | | 04/15/2022 |
| 04/15/2022 | Mendelsohn Alan | EVP & CMO | Grant | Stock Option (right to buy) | 300k | $0.31 | $92.1k | | 04/15/2022 |
| 04/15/2022 | Koconis John | CEO & Chairman | Grant | Stock Option (right to buy) | 600k | $0.31 | $184.2k | | 04/15/2022 |
| 04/15/2022 | Pirozzi Gianluca | Director | Grant | Common Stock, par value $0.001 per share | 100k | $0.00 | $0 | | 04/15/2022 |
| 04/15/2022 | Pirozzi Gianluca | Director | Grant | Stock Option (right to buy) | 100k | $0.31 | $30.7k | | 04/15/2022 |
| 03/04/2022 | Rome Zachary | Director | Payment of Exercise | Common Stock, par value $0.001 per share | 19.6k | $0.28 | $5.5k | | 03/04/2022 |
| 03/04/2022 | Rome Zachary | Director | Disposition | Value Appreciation Rights | 52.9k | $0.01 | $528.8 | | 03/04/2022 |
| 03/04/2022 | Rome Zachary | Director | Exercise | Value Appreciation Rights | 79.3k | $0.01 | $793.3 | | 03/04/2022 |
| 12/15/2021 | Koconis John | CEO & Chairman | Purchase | Common Stock, par value $0.001 per share | 20k | $0.38 | $7.7k | | 12/15/2021 |
| 11/23/2021 | Mendelsohn Alan | EVP & CMO | Purchase | Common Stock, par value $0.001 per share | 10k | $0.47 | $4.7k | | 11/23/2021 |
| 11/23/2021 | Sitar Edward J | Director | Purchase | Common Stock, par value $0.001 per share | 15k | $0.46 | $6.9k | | 11/23/2021 |
| 09/14/2021 | Koconis John | CEO & Chairman | Grant | Stock Option (right to buy) | 890k | $0.89 | $794.3k | | 09/14/2021 |
| 09/14/2021 | Rome Zachary | Director | Grant | Stock Option (right to buy) | 561k | $0.89 | $500.7k | | 09/14/2021 |
| 09/02/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 225k | $0.94 | $211k | | 09/02/2021 |
| 09/01/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 150.5k | $0.92 | $138.9k | | 08/30/2021 |
| 08/31/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 150k | $0.91 | $136.7k | | 08/30/2021 |
| 08/30/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 100k | $0.93 | $92.7k | | 08/30/2021 |
| 08/26/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 100k | $0.92 | $91.8k | | 08/24/2021 |
| 08/25/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 100k | $0.91 | $91.3k | | 08/24/2021 |
| 08/24/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 100k | $0.93 | $92.5k | | 08/24/2021 |
| 08/20/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 50k | $0.91 | $45.4k | | 08/18/2021 |
| 08/19/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 50k | $0.95 | $47.7k | | 08/18/2021 |
| 08/18/2021 | TardiMed Sciences LLC | 10% Owner | Sale | Common Stock, par value $0.001 per share | 75k | $1.00 | $75.1k | | 08/18/2021 |
| 07/01/2021 | Pirozzi Gianluca | Director | Grant | Stock Option (right to buy) | 47.6k | $1.18 | $56.2k | | 07/01/2021 |
| 07/01/2021 | Gaal Lubor | Director | Grant | Stock Option (right to buy) | 71.9k | $1.18 | $84.8k | | 07/01/2021 |
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