| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/01/2023 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Common Stock | 4k | $0.00 | $0 | | 06/01/2023 |
| 06/01/2023 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 6k | $3.70 | $22.2k | | 06/01/2023 |
| 05/18/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Stock Option (right to buy) | 3.5k | $189.87 | $655.8k | | 05/18/2023 |
| 02/23/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Restricted Stock Units | 136 | $0.00 | $0 | | 02/23/2023 |
| 10/14/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Other | Common Stock | 52.5k | $0.00 | $0 | | 10/14/2022 |
| 10/14/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Other | Common Stock | 7.2k | $0.00 | $0 | | 10/14/2022 |
| 10/14/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Disposition | Stock Option (Right to Buy) | 14k | $5.05 | $70.8k | | 10/14/2022 |
| 10/14/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Disposition | Stock Option (Right to Buy) | 28.1k | $5.43 | $152.3k | | 10/14/2022 |
| 10/14/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Disposition | Stock Option (Right to Buy) | 17.5k | $20.00 | $350.7k | | 10/14/2022 |
| 10/14/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Disposition | Stock Option (Right to Buy) | 8.4k | $25.35 | $212.3k | | 10/14/2022 |
| 10/14/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Disposition | Stock Option (Right to Buy) | 6.8k | $6.12 | $41.3k | | 10/14/2022 |
| 09/16/2022 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Common Stock | 8k | $0.00 | $0 | | 09/16/2022 |
| 09/16/2022 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 12k | $7.35 | $88.2k | | 09/16/2022 |
| 06/14/2022 | Cyclerion Therapeutics, Inc. | CYCN | Grant | Stock Option (Right to Buy) | 20k | $0.53 | $10.6k | | 06/14/2022 |
| 06/08/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Grant | Common Stock | 4.5k | $0.00 | $0 | | 06/08/2022 |
| 06/08/2022 | Forma Therapeutics Holdings, Inc. | FMTX | Grant | Stock Option (Right to Buy) | 6.8k | $6.12 | $41.3k | | 06/08/2022 |
| 06/01/2022 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 17.5k | $0.78 | $13.6k | | 06/01/2022 |
| 05/18/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Stock Option (right to buy) | 5.2k | $128.31 | $661.2k | | 05/18/2022 |
| 02/23/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Restricted Stock Units | 136 | $0.00 | $0 | | 02/23/2022 |
| 07/15/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Stock Option (right to buy) | 4k | $171.95 | $693.3k | | 07/15/2021 |
| 06/24/2021 | Cyclerion Therapeutics, Inc. | CYCN | Grant | Stock Option (Right to Buy) | 10k | $3.97 | $39.7k | | 06/24/2021 |
| 06/17/2021 | Forma Therapeutics Holdings, Inc. | FMTX | Grant | Common Stock | 2.8k | $0.00 | $0 | | 06/17/2021 |
| 06/17/2021 | Forma Therapeutics Holdings, Inc. | FMTX | Grant | Stock Option (Right to Buy) | 8.4k | $25.35 | $212.3k | | 06/17/2021 |
| 06/08/2021 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 17.5k | $6.30 | $110.2k | | 06/08/2021 |
| 07/01/2020 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Stock Option (right to buy) | 4.6k | $148.77 | $681.5k | | 07/01/2020 |
| 06/23/2020 | Forma Therapeutics Holdings, Inc. | FMTX | Purchase | Common Stock | 52.5k | $0.00 | $0 | | 06/23/2020 |
| 06/23/2020 | Forma Therapeutics Holdings, Inc. | FMTX | Sale | Enterprise 2 Junior Stock | 33.8k | $0.00 | $0 | | 06/23/2020 |
| 06/23/2020 | Forma Therapeutics Holdings, Inc. | FMTX | Sale | Enterprise 3 Junior Stock | 9.8k | $0.00 | $0 | | 06/23/2020 |
| 06/23/2020 | Forma Therapeutics Holdings, Inc. | FMTX | Sale | Enterprise 4 Junior Stock | 10.2k | $0.00 | $0 | | 06/23/2020 |
| 06/23/2020 | Forma Therapeutics Holdings, Inc. | FMTX | Sale | Enterprise 5 Junior Stock | 14k | $0.00 | $0 | | 06/23/2020 |
| 06/18/2020 | Forma Therapeutics Holdings, Inc. | FMTX | Grant | Stock Option (Right to Buy) | 17.5k | $20.00 | $350.7k | | 06/18/2020 |
| 06/16/2020 | Cyclerion Therapeutics, Inc. | CYCN | Grant | Stock Option (Right to Buy) | 10k | $4.46 | $44.6k | | 06/16/2020 |
| 06/11/2020 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 17.5k | $9.17 | $160.5k | | 06/11/2020 |
| 11/20/2019 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 75k | $100.00 | $7.5M | | 11/20/2019 |
| 11/20/2019 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Non-Qualified Stock Option (right to buy) | 30k | $9.14 | $274.2k | | 11/20/2019 |
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