| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/03/2023 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Restricted Stock Unit (2017 Plan) | 20k | $0.00 | $0 | | 01/03/2023 |
| 08/03/2022 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Restricted Stock Unit (2017 Plan) | 4.7k | $0.00 | $0 | | 08/03/2022 |
| 08/03/2022 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Restricted Stock Unit (2017 Plan) | 20k | $0.00 | $0 | | 08/03/2022 |
| 03/16/2022 | ACURA PHARMACEUTICALS, INC | ACUR | Grant | | 40k | $0.00 | $0 | | 03/16/2022 |
| 02/24/2021 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | | 20k | $0.00 | $0 | | 02/24/2021 |
| 02/24/2021 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 7.6k | $0.40 | $3k | | 02/24/2021 |
| 02/24/2021 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Common Stock | 20k | $0.15 | $3k | | 02/24/2021 |
| 01/02/2020 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Restricted Stock Unit (2017 Plan) | 4.7k | $0.00 | $0 | | 01/02/2020 |
| 12/11/2018 | ACURA PHARMACEUTICALS, INC | ACUR | Grant | | 60k | $0.00 | $0 | | 12/11/2018 |
| 12/11/2018 | ACURA PHARMACEUTICALS, INC | ACUR | Grant | | 20k | $0.00 | $0 | | 12/11/2018 |
| 12/14/2017 | ACURA PHARMACEUTICALS, INC | ACUR | Purchase | Common Stock | 300k | $0.10 | $30k | | 12/14/2017 |
| 12/11/2017 | ACURA PHARMACEUTICALS, INC | ACUR | Grant | | 14k | $0.00 | $0 | | 12/11/2017 |
| 02/07/2017 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Common Stock | 1.2k | $0.92 | $1.1k | | 02/07/2017 |
| 02/07/2017 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 821 | $1.30 | $1.1k | | 02/07/2017 |
| 02/07/2017 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Stock Options | 1.2k | $0.00 | $0 | | 02/07/2017 |
| 12/08/2016 | ACURA PHARMACEUTICALS, INC | ACUR | Grant | Stock Options | 14k | $0.00 | $0 | | 12/08/2016 |
| 01/16/2014 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Stock Options | 6.2k | $1.30 | $8.1k | | 01/16/2014 |
| 01/16/2014 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 694 | $1.82 | $1.3k | | 01/16/2014 |
| 01/16/2014 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 4.4k | $1.82 | $8.1k | | 01/16/2014 |
| 01/01/2014 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 283 | $1.67 | $472.6 | | 01/01/2014 |
| 01/01/2014 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 23.7k | $1.67 | $39.5k | | 01/01/2014 |
| 12/12/2013 | ACURA PHARMACEUTICALS, INC | ACUR | Grant | Stock Options | 37.5k | $0.00 | $0 | | 12/12/2013 |
| 03/05/2013 | ACURA PHARMACEUTICALS, INC | ACUR | Exercise | Stock Options | 6.2k | $1.30 | $8.1k | | 03/05/2013 |
| 03/05/2013 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 1.3k | $3.04 | $3.9k | | 03/05/2013 |
| 03/05/2013 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 2.7k | $3.04 | $8.1k | | 03/05/2013 |
| 12/15/2011 | ACURA PHARMACEUTICALS, INC | ACUR | Grant | Stock Options | 35k | $0.00 | $0 | | 12/15/2011 |
| 01/01/2011 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 143 | $3.31 | $473.3 | | 01/01/2011 |
| 01/01/2011 | ACURA PHARMACEUTICALS, INC | ACUR | Payment of Exercise | Common Stock | 19.8k | $3.31 | $65.4k | | 01/01/2011 |