| In millions, except per share items | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 | Dec-31-14 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues: |
| Partnered product sales | 46.7 | 51.0 | 52.9 | | | | | |
| Proprietary product sales, net | 80.0 | 62.9 | 39.2 | | | | | |
| UNITED STATES | | | | 57.0 | 48.9 | | | |
| Partnered Product | | | | 30.3 | 23.7 | | | |
| Other | 57.3 | 35.8 | 31.8 | | | | | |
| Total revenues [+] | 184.0 | 149.6 | 123.9 | 63.6 | 54.5 | 52.2 | 45.7 | 26.5 |
| Licensing | | | | | | | 7.2 | 3.7 |
| Royalties | | | | | | | 2.0 | 2.4 |
| Products | | | | | | | 27.5 | 13.2 |
| Contracts | | | | | | | 8.9 | 7.2 |
| Revenue growth [+] | 23.0% | 20.8% | 94.9% | 16.6% | 4.4% | 14.4% | 72.3% | 28.5% |
| Partnered product sales | -8.4% | -3.7% | | | | | | |
| Proprietary product sales, net | 27.3% | 60.3% | | | | | | |
| UNITED STATES | | | | 16.6% | | | | |
| Partnered Product | | | | 27.7% | | | | |
| Proprietary Product | | | | -2.3% | | | | |
| Cost of goods sold [+] | 29.7 | 63.1 | 50.5 | 18.6 | 27.5 | 28.8 | 19.5 | 11.2 |
| Cost of product sales | | | | | | | 12.9 | 9.4 |
| Contract costs | | | | | | | 6.5 | 1.9 |
| Gross profit | 154.3 | 86.5 | 73.4 | 45.0 | 27.0 | 23.4 | 26.2 | 15.3 |
| Gross margin | 83.9% | 57.8% | 59.2% | 70.8% | 49.6% | 44.8% | 57.4% | 57.6% |
| Selling, general and administrative | 73.9 | 62.8 | 61.8 | 36.8 | 31.6 | 27.9 | 26.9 | 31.7 |
| Research and development | 14.5 | 10.1 | 10.6 | 12.3 | 11.9 | 19.6 | 19.7 | 18.6 |
| Other operating expenses | -38.6 | | | -12.5 | -1.7 | | | |
| EBITDA [+] | 108.4 | 16.2 | 3.5 | 11.1 | -12.6 | -22.3 | -18.9 | -33.9 |
| EBITDA growth | 567.4% | 357.8% | -68.1% | -188.1% | -43.3% | 18.0% | -44.3% | 67.0% |
| EBITDA margin | 58.9% | 10.9% | 2.9% | 17.5% | -23.2% | -42.6% | -41.3% | -127.9% |
| Depreciation | 3.9 | 2.6 | 2.6 | 2.7 | 2.1 | 1.9 | 1.6 | 1.2 |
| EBITA | 104.5 | 13.6 | 1.0 | 8.4 | -14.7 | -24.1 | -20.4 | -35.1 |
| EBITA margin | 56.8% | 9.1% | 0.8% | 13.2% | -27.0% | -46.2% | -44.7% | -132.5% |
| Amortization of intangibles | | | | | | | 0.0 | |
| EBIT [+] | 104.5 | 13.6 | 1.0 | 8.4 | -14.7 | -24.1 | -20.5 | -35.1 |
| EBIT growth | 667.5% | 1272.9% | -88.2% | -157.0% | -38.9% | 17.9% | -41.7% | 68.4% |
| EBIT margin | 56.8% | 9.1% | 0.8% | 13.2% | -27.0% | -46.2% | -44.8% | -132.5% |
| Non-recurring items [+] | 38.6 | | | 12.5 | 0.9 | | | |
| Loss (gain) on sale of assets | 38.6 | | | 12.5 | 0.9 | | | |
| Interest expense, net [+] | 3.6 | 3.8 | 3.5 | 2.7 | 1.4 | | | -0.1 |
| Interest expense | 3.6 | 3.8 | 3.5 | 2.7 | 1.4 | | | |
| Interest income | | | | | | | | 0.1 |
| Other income (expense), net [+] | -0.1 | 0.1 | 0.5 | 0.3 | 0.3 | -0.1 | 0.0 | -0.1 |
| Gain (loss) on foreign currency transactions | | | | | | | | 0.0 |
| Other | -0.1 | 0.1 | 0.5 | 0.3 | 0.3 | -0.1 | 0.0 | -0.1 |
| Pre-tax income | 62.3 | 9.9 | -2.0 | -6.5 | -16.7 | -24.2 | -20.5 | -35.1 |
| Income taxes | 16.0 | -46.3 | 0.0 | 0.0 | 0.0 | 0.1 | 0.2 | 0.0 |
| Tax rate | 25.7% | | 0.0% | 0.0% | 0.0% | | | |
| Net income | 46.3 | 56.2 | -2.0 | -6.5 | -16.7 | -24.3 | -20.7 | -35.2 |
| Net margin | 25.2% | 37.6% | -1.6% | -10.3% | -30.7% | -46.6% | -45.2% | -132.6% |
| |
| Basic EPS [+] | $0.27 | $0.34 | ($0.01) | ($0.04) | ($0.11) | ($0.16) | ($0.14) | ($0.27) |
| Growth | -19.2% | -2814.3% | -69.9% | -61.4% | -31.7% | 11.4% | -47.7% | 66.6% |
| Diluted EPS [+] | $0.26 | $0.33 | ($0.01) | ($0.04) | ($0.11) | ($0.16) | ($0.14) | ($0.27) |
| Growth | -19.8% | -2749.1% | -69.9% | -61.4% | -31.7% | 11.4% | -47.7% | 66.6% |
| |
| Shares outstanding (basic) [+] | 169.2 | 166.1 | 162.6 | 157.4 | 156.1 | 155.0 | 146.6 | 130.5 |
| Growth | 1.9% | 2.1% | 3.3% | 0.9% | 0.7% | 5.7% | 12.3% | 2.9% |
| Shares outstanding (diluted) [+] | 174.7 | 170.2 | 162.6 | 157.4 | 156.1 | 155.0 | 146.6 | 130.5 |
| Growth | 2.7% | 4.7% | 3.3% | 0.9% | 0.7% | 5.7% | 12.3% | 2.9% |
| |
| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |