The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
Adobe Inc | Common Stock | 00724F101 | 15,766 | 33,165 | SH | SOLE | 33,165 | 0 | 0 | ||
Aerojet Rocketdyne Holdings Inc | Common Stock | 007800105 | 4,228 | 90,029 | SH | SOLE | 90,029 | 0 | 0 | ||
AeroVironment Inc | Common Stock | 008073108 | 65,079 | 560,739 | SH | SOLE | 560,739 | 0 | 0 | ||
Alibaba Group Holding Ltd | ADR | 01609W102 | 133,958 | 590,826 | SH | SOLE | 590,826 | 0 | 0 | ||
Align Technology Inc | Common Stock | 016255101 | 6,615 | 12,215 | SH | SOLE | 12,215 | 0 | 0 | ||
Allegheny Technologies Inc | Common Stock | 01741R102 | 746 | 35,406 | SH | SOLE | 35,406 | 0 | 0 | ||
Alphabet Inc | Common Stock | 02079K107 | 119,041 | 57,546 | SH | SOLE | 57,546 | 0 | 0 | ||
Altair Engineering Inc | Common Stock | 021369103 | 24,201 | 386,786 | SH | SOLE | 386,786 | 0 | 0 | ||
Amazon.com Inc | Common Stock | 023135106 | 43,063 | 13,918 | SH | SOLE | 13,918 | 0 | 0 | ||
AMETEK Inc | Common Stock | 031100100 | 7,197 | 56,347 | SH | SOLE | 56,347 | 0 | 0 | ||
ANSYS Inc | Common Stock | 03662Q105 | 57,539 | 169,452 | SH | SOLE | 169,452 | 0 | 0 | ||
Apple Inc | Common Stock | 037833100 | 72,562 | 594,039 | SH | SOLE | 594,039 | 0 | 0 | ||
AquaBounty Technologies Inc | Common Stock | 03842K200 | 48,557 | 7,247,378 | SH | SOLE | 7,247,378 | 0 | 0 | ||
Arcturus Therapeutics Holdings Inc | Common Stock | 03969T109 | 137,607 | 3,331,889 | SH | SOLE | 3,331,889 | 0 | 0 | ||
Autodesk Inc | Common Stock | 052769106 | 41,862 | 151,043 | SH | SOLE | 151,043 | 0 | 0 | ||
Baidu Inc | ADR | 056752108 | 1,115,497 | 5,127,543 | SH | SOLE | 4,688,247 | 329,127 | 110,169 | ||
Renishaw PLC | Common Stock | G75006117 | 27,726 | 313,442 | SH | SOLE | 313,442 | 0 | 0 | ||
CareDx Inc | Common Stock | 14167L103 | 303,738 | 4,460,824 | SH | SOLE | 4,460,824 | 0 | 0 | ||
Carpenter Technology Corp | Common Stock | 144285103 | 750 | 18,218 | SH | SOLE | 18,218 | 0 | 0 | ||
Castle Biosciences Inc | Common Stock | 14843C105 | 177,810 | 2,597,288 | SH | SOLE | 2,597,288 | 0 | 0 | ||
Cellectis SA | ADR | 15117K103 | 103,425 | 5,117,526 | SH | SOLE | 5,117,526 | 0 | 0 | ||
Cerus Corp | Common Stock | 157085101 | 153,507 | 25,541,955 | SH | SOLE | 23,600,810 | 616,222 | 1,324,923 | ||
Codexis Inc | Common Stock | 192005106 | 143,786 | 6,281,617 | SH | SOLE | 6,281,617 | 0 | 0 | ||
Deere & Co | Common Stock | 244199105 | 132,551 | 354,282 | SH | SOLE | 354,282 | 0 | 0 | ||
DuPont de Nemours Inc | Common Stock | 26614N102 | 603 | 7,808 | SH | SOLE | 7,808 | 0 | 0 | ||
Eastman Chemical Co | Common Stock | 277432100 | 658 | 5,978 | SH | SOLE | 5,978 | 0 | 0 | ||
Editas Medicine Inc | Common Stock | 28106W103 | 367,581 | 8,751,923 | SH | SOLE | 7,487,570 | 1,033,435 | 230,918 | ||
ExOne Co/The | Common Stock | 302104104 | 83,948 | 2,676,905 | SH | SOLE | 2,413,344 | 0 | 263,561 | ||
Facebook Inc | Common Stock | 30303M102 | 90,429 | 307,029 | SH | SOLE | 307,029 | 0 | 0 | ||
FARO Technologies Inc | Common Stock | 311642102 | 7,935 | 91,661 | SH | SOLE | 91,661 | 0 | 0 | ||
Fate Therapeutics Inc | Common Stock | 31189P102 | 540,422 | 6,554,546 | SH | SOLE | 6,554,546 | 0 | 0 | ||
General Electric Co | Common Stock | 369604103 | 5,483 | 417,583 | SH | SOLE | 417,583 | 0 | 0 | ||
Grayscale Bitcoin Trust BTC | Open-End Fund | 389637109 | 434,141 | 8,675,881 | SH | SOLE | 8,011,293 | 658,408 | 6,180 | ||
Guardant Health Inc | Common Stock | 40131M109 | 107,351 | 703,250 | SH | SOLE | 703,250 | 0 | 0 | ||
Guidewire Software Inc | Common Stock | 40171V100 | 41,604 | 409,367 | SH | SOLE | 409,367 | 0 | 0 | ||
HDFC Bank Ltd | ADR | 40415F101 | 42,452 | 546,426 | SH | SOLE | 546,426 | 0 | 0 | ||
HP Inc | Common Stock | 40434L105 | 31,288 | 985,456 | SH | SOLE | 985,456 | 0 | 0 | ||
Hexcel Corp | Common Stock | 428291108 | 745 | 13,307 | SH | SOLE | 13,307 | 0 | 0 | ||
HubSpot Inc | Common Stock | 443573100 | 74,136 | 163,219 | SH | SOLE | 163,219 | 0 | 0 | ||
Incyte Corp | Common Stock | 45337C102 | 242,847 | 2,988,149 | SH | SOLE | 2,988,149 | 0 | 0 | ||
Intellia Therapeutics Inc | Common Stock | 45826J105 | 771,404 | 9,611,911 | SH | SOLE | 7,778,015 | 1,427,842 | 406,054 | ||
Interactive Brokers Group Inc | Common Stock | 45841N107 | 219 | 3,002 | SH | SOLE | 3,002 | 0 | 0 | ||
Intercontinental Exchange Inc | Common Stock | 45866F104 | 627,317 | 5,617,092 | SH | SOLE | 5,268,406 | 259,279 | 89,407 | ||
Intuit Inc | Common Stock | 461202103 | 76,489 | 199,680 | SH | SOLE | 199,680 | 0 | 0 | ||
Intuitive Surgical Inc | Common Stock | 46120E602 | 36,840 | 49,855 | SH | SOLE | 49,855 | 0 | 0 | ||
OC Oerlikon Corp AG | Common Stock | H59187106 | 5,364 | 462,333 | SH | SOLE | 462,333 | 0 | 0 | ||
Invitae Corp | Common Stock | 46185L103 | 916,192 | 23,977,808 | SH | SOLE | 20,810,440 | 2,373,199 | 794,169 | ||
Ionis Pharmaceuticals Inc | Common Stock | 462222100 | 231,197 | 5,142,271 | SH | SOLE | 5,142,271 | 0 | 0 | ||
Iovance Biotherapeutics Inc | Common Stock | 462260100 | 624,546 | 19,726,650 | SH | SOLE | 18,981,913 | 466,145 | 278,592 | ||
Iridium Communications Inc | Common Stock | 46269C102 | 427,150 | 10,355,147 | SH | SOLE | 9,466,700 | 705,771 | 182,676 | ||
JD.com Inc | ADR | 47215P106 | 392,282 | 4,651,745 | SH | SOLE | 4,651,745 | 0 | 0 | ||
SGL Carbon SE | Common Stock | D6949M108 | 788 | 112,500 | SH | SOLE | 112,500 | 0 | 0 | ||
Kaiser Aluminum Corp | Common Stock | 483007704 | 5,086 | 46,030 | SH | SOLE | 46,030 | 0 | 0 | ||
Komatsu Ltd | ADR | 500458401 | 106,587 | 3,412,965 | SH | SOLE | 3,412,965 | 0 | 0 | ||
Kratos Defense & Security Solutions Inc | Common Stock | 50077B207 | 143,000 | 5,241,941 | SH | SOLE | 5,241,941 | 0 | 0 | ||
Henkel AG & Co KGaA | Preference | D3207M110 | 689 | 5,962 | SH | SOLE | 5,962 | 0 | 0 | ||
Bertrandt AG | Common Stock | D1014N107 | 4,900 | 90,559 | SH | SOLE | 90,559 | 0 | 0 | ||
LendingClub Corp | Common Stock | 52603A208 | 120,074 | 7,268,414 | SH | SOLE | 6,466,326 | 183,369 | 618,719 | ||
LendingTree Inc | Common Stock | 52603B107 | 367,018 | 1,723,091 | SH | SOLE | 1,489,736 | 177,145 | 56,210 | ||
Dassault Systemes SE | Common Stock | F2457H472 | 27,110 | 126,494 | SH | SOLE | 126,494 | 0 | 0 | ||
Lincoln Electric Holdings Inc | Common Stock | 533900106 | 4,863 | 39,556 | SH | SOLE | 39,556 | 0 | 0 | ||
Siemens AG | Common Stock | D69671218 | 5,410 | 32,880 | SH | SOLE | 32,880 | 0 | 0 | ||
Materialise NV | ADR | 57667T100 | 267,533 | 7,441,821 | SH | SOLE | 7,177,635 | 75,126 | 189,060 | ||
MercadoLibre Inc | Common Stock | 58733R102 | 188,842 | 128,277 | SH | SOLE | 119,102 | 9,175 | 0 | ||
Microsoft Corp | Common Stock | 594918104 | 25,739 | 109,170 | SH | SOLE | 109,170 | 0 | 0 | ||
Bezeq The Israeli Telecommunication Corp Ltd | Common Stock | M2012Q100 | 6,297 | 5,896,764 | SH | SOLE | 5,896,764 | 0 | 0 | ||
Moog Inc | Common Stock | 615394202 | 4,879 | 58,675 | SH | SOLE | 58,675 | 0 | 0 | ||
Danel Adir Yeoshua Ltd | Common Stock | M27013107 | 6,706 | 40,911 | SH | SOLE | 40,911 | 0 | 0 | ||
Hilan Ltd | Common Stock | M5299H123 | 6,311 | 133,407 | SH | SOLE | 133,407 | 0 | 0 | ||
Nano Dimension Ltd | ADR | 63008G203 | 111,389 | 12,967,241 | SH | SOLE | 12,967,241 | 0 | 0 | ||
NanoString Technologies Inc | Common Stock | 63009R109 | 217,825 | 3,314,947 | SH | SOLE | 3,193,514 | 121,433 | 0 | ||
Elbit Systems Ltd | Common Stock | M3760D101 | 49,232 | 344,279 | SH | SOLE | 344,279 | 0 | 0 | ||
SBI Holdings Inc/Japan | Common Stock | J6991H100 | 171 | 6,300 | SH | SOLE | 6,300 | 0 | 0 | ||
Partner Communications Co Ltd | Common Stock | M78465107 | 6,310 | 1,304,896 | SH | SOLE | 1,304,896 | 0 | 0 | ||
Netflix Inc | Common Stock | 64110L106 | 69,642 | 133,501 | SH | SOLE | 133,501 | 0 | 0 | ||
Nice Ltd | ADR | 653656108 | 4,905 | 22,504 | SH | SOLE | 22,504 | 0 | 0 | ||
FirstRand Ltd | Common Stock | S5202Z131 | 30 | 13,580 | SH | SOLE | 13,580 | 0 | 0 | ||
NVIDIA Corp | Common Stock | 67066G104 | 216,303 | 405,115 | SH | SOLE | 405,115 | 0 | 0 | ||
NuVasive Inc | Common Stock | 670704105 | 5,331 | 81,321 | SH | SOLE | 81,321 | 0 | 0 | ||
Matrix IT Ltd | Common Stock | M6859E153 | 6,376 | 266,444 | SH | SOLE | 266,444 | 0 | 0 | ||
Toray Industries Inc | Common Stock | J89494116 | 609 | 94,508 | SH | SOLE | 94,508 | 0 | 0 | ||
PTC Inc | Common Stock | 69370C100 | 26,027 | 189,081 | SH | SOLE | 189,081 | 0 | 0 | ||
Pacific Biosciences of California Inc | Common Stock | 69404D108 | 709,543 | 21,301,191 | SH | SOLE | 20,654,514 | 413,947 | 232,730 | ||
One Software Technologies Ltd | Common Stock | M75260113 | 6,327 | 48,615 | SH | SOLE | 48,615 | 0 | 0 | ||
PayPal Holdings Inc | Common Stock | 70450Y103 | 407,881 | 1,679,629 | SH | SOLE | 1,558,336 | 110,602 | 10,691 | ||
Personalis Inc | Common Stock | 71535D106 | 140,420 | 5,705,827 | SH | SOLE | 5,705,827 | 0 | 0 | ||
Straumann Holding AG | Common Stock | H8300N119 | 27,109 | 21,662 | SH | SOLE | 21,662 | 0 | 0 | ||
Pinduoduo Inc | ADR | 722304102 | 112,078 | 837,156 | SH | SOLE | 837,156 | 0 | 0 | ||
Pinterest Inc | Common Stock | 72352L106 | 229,119 | 3,094,949 | SH | SOLE | 3,094,949 | 0 | 0 | ||
Pluristem Therapeutics Inc | Common Stock | 72940R300 | 17,121 | 3,589,322 | SH | SOLE | 3,589,322 | 0 | 0 | ||
Proto Labs Inc | Common Stock | 743713109 | 444,978 | 3,654,854 | SH | SOLE | 3,126,453 | 386,403 | 141,998 | ||
Redhill Biopharma Ltd | ADR | 757468103 | 5,678 | 775,698 | SH | SOLE | 775,698 | 0 | 0 | ||
Roku Inc | Common Stock | 77543R102 | 1,628,082 | 4,997,644 | SH | SOLE | 4,429,891 | 447,706 | 120,047 | ||
Charles Schwab Corp/The | Common Stock | 808513105 | 46,557 | 714,287 | SH | SOLE | 714,287 | 0 | 0 | ||
Seres Therapeutics Inc | Common Stock | 81750R102 | 244,114 | 11,855,947 | SH | SOLE | 10,210,569 | 1,341,432 | 303,946 | ||
Shopify Inc | Common Stock | 82509L107 | 1,187,853 | 1,073,523 | SH | SOLE | 992,842 | 64,581 | 16,100 | ||
Snap Inc | Common Stock | 83304A106 | 165,966 | 3,173,955 | SH | SOLE | 3,173,955 | 0 | 0 | ||
Splunk Inc | Common Stock | 848637104 | 1,194 | 8,813 | SH | SOLE | 8,813 | 0 | 0 | ||
Square Inc | Common Stock | 852234103 | 2,492,627 | 10,978,316 | SH | SOLE | 10,014,653 | 737,361 | 226,302 | ||
Stryker Corp | Common Stock | 863667101 | 4,662 | 19,138 | SH | SOLE | 19,138 | 0 | 0 | ||
Syros Pharmaceuticals Inc | Common Stock | 87184Q107 | 57,684 | 7,711,724 | SH | SOLE | 7,032,971 | 186,593 | 492,160 | ||
Taiwan Semiconductor Manufacturing Co Ltd | ADR | 874039100 | 47,019 | 397,524 | SH | SOLE | 397,524 | 0 | 0 | ||
Teladoc Health Inc | Common Stock | 87918A105 | 2,621,595 | 14,424,180 | SH | SOLE | 13,420,301 | 771,257 | 232,622 | ||
Tencent Holdings Ltd | ADR | 88032Q109 | 548,025 | 6,867,476 | SH | SOLE | 6,438,407 | 373,500 | 55,569 | ||
Teradyne Inc | Common Stock | 880770102 | 350,086 | 2,877,103 | SH | SOLE | 2,779,946 | 58,658 | 38,499 | ||
Tesla Inc | Common Stock | 88160R101 | 3,864,324 | 5,785,523 | SH | SOLE | 5,351,827 | 429,044 | 4,652 | ||
Teva Pharmaceutical Industries Ltd | ADR | 881624209 | 5,768 | 499,844 | SH | SOLE | 499,844 | 0 | 0 | ||
Trade Desk Inc/The | Common Stock | 88339J105 | 121,241 | 186,049 | SH | SOLE | 186,049 | 0 | 0 | ||
3D Systems Corp | Common Stock | 88554D205 | 58,819 | 2,143,547 | SH | SOLE | 2,143,547 | 0 | 0 | ||
3M Co | Common Stock | 88579Y101 | 731 | 3,792 | SH | SOLE | 3,792 | 0 | 0 | ||
Trimble Inc | Common Stock | 896239100 | 218,609 | 2,810,249 | SH | SOLE | 2,810,249 | 0 | 0 | ||
Twilio Inc | Common Stock | 90138F102 | 932,715 | 2,737,162 | SH | SOLE | 2,482,948 | 208,592 | 45,622 | ||
Twist Bioscience Corp | Common Stock | 90184D100 | 748,798 | 6,045,520 | SH | SOLE | 5,796,015 | 139,968 | 109,537 | ||
2U Inc | Common Stock | 90214J101 | 452,531 | 11,837,072 | SH | SOLE | 9,936,908 | 1,449,362 | 450,802 | ||
Ultra Clean Holdings Inc | Common Stock | 90385V107 | 6,944 | 119,648 | SH | SOLE | 119,648 | 0 | 0 | ||
United Parcel Service Inc | Common Stock | 911312106 | 4,887 | 28,750 | SH | SOLE | 28,750 | 0 | 0 | ||
Veracyte Inc | Common Stock | 92337F107 | 409,429 | 7,617,287 | SH | SOLE | 7,404,211 | 213,076 | 0 | ||
Verisk Analytics Inc | Common Stock | 92345Y106 | 634 | 3,588 | SH | SOLE | 3,588 | 0 | 0 | ||
Workday Inc | Common Stock | 98138H101 | 81,293 | 327,228 | SH | SOLE | 327,228 | 0 | 0 | ||
Xilinx Inc | Common Stock | 983919101 | 29,942 | 241,660 | SH | SOLE | 241,660 | 0 | 0 | ||
Xerox Holdings Corp | Common Stock | 98421M106 | 687 | 28,303 | SH | SOLE | 28,303 | 0 | 0 | ||
Zillow Group Inc | Common Stock | 98954M200 | 1,300,633 | 10,032,650 | SH | SOLE | 9,104,846 | 721,655 | 206,149 | ||
Koninklijke DSM NV | Common Stock | N5017D122 | 615 | 3,625 | SH | SOLE | 3,625 | 0 | 0 | ||
Arkema SA | Common Stock | F0392W125 | 660 | 5,435 | SH | SOLE | 5,435 | 0 | 0 | ||
MGI Digital Graphic Technology | Common Stock | F4090S113 | 23,904 | 412,659 | SH | SOLE | 412,659 | 0 | 0 | ||
Sandvik AB | Common Stock | W74857165 | 681 | 24,871 | SH | SOLE | 24,871 | 0 | 0 | ||
Hexagon AB | Common Stock | W40063104 | 7,031 | 76,061 | SH | SOLE | 76,061 | 0 | 0 | ||
Cellcom Israel Ltd | Common Stock | M2196U109 | 4,983 | 1,332,925 | SH | SOLE | 1,332,925 | 0 | 0 | ||
Evonik Industries AG | Common Stock | D2R90Y117 | 702 | 19,793 | SH | SOLE | 19,793 | 0 | 0 | ||
Fattal Holdings 1998 Ltd | Common Stock | M4148G105 | 6,150 | 56,905 | SH | SOLE | 56,905 | 0 | 0 | ||
Meituan | Common Stock | G59669104 | 87,854 | 2,290,458 | SH | SOLE | 2,290,458 | 0 | 0 | ||
SLM Solutions Group AG | Common Stock | D6T690109 | 22,106 | 1,064,114 | SH | SOLE | 1,064,114 | 0 | 0 | ||
ZhongAn Online P&C Insurance Co Ltd | Common Stock | Y989DF109 | 114,265 | 18,941,138 | SH | SOLE | 18,941,138 | 0 | 0 | ||
Adyen NV | Common Stock | N3501V104 | 128,337 | 57,380 | SH | SOLE | 57,380 | 0 | 0 | ||
Atlassian Corp PLC | Common Stock | G06242104 | 60,114 | 285,226 | SH | SOLE | 285,226 | 0 | 0 | ||
Medtronic PLC | Common Stock | G5960L103 | 4,701 | 39,796 | SH | SOLE | 39,796 | 0 | 0 | ||
Sapiens International Corp NV | Common Stock | G7T16G103 | 5,816 | 182,947 | SH | SOLE | 182,947 | 0 | 0 | ||
CRISPR Therapeutics AG | Common Stock | H17182108 | 1,010,179 | 8,290,350 | SH | SOLE | 7,367,516 | 704,010 | 218,824 | ||
Spotify Technology SA | Common Stock | L8681T102 | 1,042,681 | 3,891,325 | SH | SOLE | 3,510,239 | 289,115 | 91,971 | ||
Allot Ltd | Common Stock | M0854Q105 | 6,886 | 431,153 | SH | SOLE | 431,153 | 0 | 0 | ||
AudioCodes Ltd | Common Stock | M15342104 | 5,121 | 189,795 | SH | SOLE | 189,795 | 0 | 0 | ||
Camtek Ltd/Israel | Common Stock | M20791105 | 7,711 | 257,883 | SH | SOLE | 257,883 | 0 | 0 | ||
Ceragon Networks Ltd | Common Stock | M22013102 | 4,378 | 1,161,214 | SH | SOLE | 1,161,214 | 0 | 0 | ||
Check Point Software Technologies Ltd | Common Stock | M22465104 | 5,372 | 47,974 | SH | SOLE | 47,974 | 0 | 0 | ||
Compugen Ltd | Common Stock | M25722105 | 123,888 | 14,422,362 | SH | SOLE | 14,070,300 | 219,844 | 132,218 | ||
CyberArk Software Ltd | Common Stock | M2682V108 | 4,787 | 37,011 | SH | SOLE | 37,011 | 0 | 0 | ||
Evogene Ltd | Common Stock | M4119S104 | 24,175 | 4,796,679 | SH | SOLE | 4,796,679 | 0 | 0 | ||
Fiverr International Ltd | Common Stock | M4R82T106 | 5,367 | 24,713 | SH | SOLE | 24,713 | 0 | 0 | ||
Ituran Location and Control Ltd | Common Stock | M6158M104 | 6,770 | 318,892 | SH | SOLE | 318,892 | 0 | 0 | ||
Nova Measuring Instruments Ltd | Common Stock | M7516K103 | 6,845 | 75,210 | SH | SOLE | 75,210 | 0 | 0 | ||
Radware Ltd | Common Stock | M81873107 | 5,706 | 218,772 | SH | SOLE | 218,772 | 0 | 0 | ||
Stratasys Ltd | Common Stock | M85548101 | 269,885 | 10,420,260 | SH | SOLE | 8,139,415 | 1,527,641 | 753,204 | ||
Taro Pharmaceutical Industries Ltd | Common Stock | M8737E108 | 5,799 | 78,627 | SH | SOLE | 78,627 | 0 | 0 | ||
Tower Semiconductor Ltd | Common Stock | M87915274 | 5,522 | 196,917 | SH | SOLE | 196,917 | 0 | 0 | ||
UroGen Pharma Ltd | Common Stock | M96088105 | 5,686 | 291,870 | SH | SOLE | 291,870 | 0 | 0 | ||
Wix.com Ltd | Common Stock | M98068105 | 6,733 | 24,114 | SH | SOLE | 24,114 | 0 | 0 | ||
NXP Semiconductors NV | Common Stock | N6596X109 | 116,862 | 580,421 | SH | SOLE | 580,421 | 0 | 0 | ||
DocuSign Inc | Common Stock | 256163106 | 647,378 | 3,197,720 | SH | SOLE | 3,056,146 | 106,151 | 35,423 | ||
Zscaler Inc | Common Stock | 98980G102 | 107 | 621 | SH | SOLE | 621 | 0 | 0 | ||
GMO internet Inc | Common Stock | J1822R104 | 23 | 800 | SH | SOLE | 800 | 0 | 0 | ||
Discovery Ltd | Common Stock | S2192Y109 | 48,849 | 5,438,981 | SH | SOLE | 5,438,981 | 0 | 0 | ||
Inmode Ltd | Common Stock | M5425M103 | 7,379 | 101,962 | SH | SOLE | 101,962 | 0 | 0 | ||
Perion Network Ltd | Common Stock | M78673114 | 8,086 | 451,724 | SH | SOLE | 451,724 | 0 | 0 | ||
Silvergate Capital Corp | Common Stock | 82837P408 | 275,720 | 1,939,369 | SH | SOLE | 1,939,369 | 0 | 0 | ||
Meituan | ADR | 58533E103 | 161 | 2,055 | SH | SOLE | 2,055 | 0 | 0 | ||
Z Holdings Corp | Common Stock | J9894K105 | 71,151 | 14,293,530 | SH | SOLE | 14,293,530 | 0 | 0 | ||
Sea Ltd | ADR | 81141R100 | 707,879 | 3,171,074 | SH | SOLE | 2,924,996 | 188,718 | 57,360 | ||
Z Holdings Corp | ADR | 98877X101 | 567 | 57,245 | SH | SOLE | 57,245 | 0 | 0 | ||
Pure Storage Inc | Common Stock | 74624M102 | 708,402 | 32,887,736 | SH | SOLE | 29,671,107 | 2,638,808 | 577,821 | ||
Synopsys Inc | Common Stock | 871607107 | 381,024 | 1,537,753 | SH | SOLE | 1,469,312 | 45,794 | 22,647 | ||
HUYA Inc | ADR | 44852D108 | 214,054 | 10,988,392 | SH | SOLE | 10,020,754 | 735,617 | 232,021 | ||
RADA Electronic Industries Ltd | Common Stock | M81863124 | 6,955 | 579,065 | SH | SOLE | 579,065 | 0 | 0 | ||
PagerDuty Inc | Common Stock | 69553P100 | 401,600 | 9,982,602 | SH | SOLE | 8,614,212 | 1,041,802 | 326,588 | ||
Caterpillar Inc | Common Stock | 149123101 | 88,567 | 381,967 | SH | SOLE | 381,967 | 0 | 0 | ||
Arconic Corp | Common Stock | 03966V107 | 3,965 | 156,152 | SH | SOLE | 156,152 | 0 | 0 | ||
Lightspeed POS Inc | Common Stock | 53227R106 | 1,054 | 16,774 | SH | SOLE | 16,774 | 0 | 0 | ||
Adaptive Biotechnologies Corp | Common Stock | 00650F109 | 139,860 | 3,473,910 | SH | SOLE | 3,473,910 | 0 | 0 | ||
10X Genomics Inc | Common Stock | 88025U109 | 634,246 | 3,504,121 | SH | SOLE | 3,168,614 | 263,960 | 71,547 | ||
Crowdstrike Holdings Inc | Common Stock | 22788C105 | 60,981 | 334,124 | SH | SOLE | 334,124 | 0 | 0 | ||
Bitcoin Fund/The | Closed-End Fund | 09175G104 | 12,887 | 199,331 | SH | SOLE | 0 | 0 | 199,331 | ||
Schrodinger Inc/United States | Common Stock | 80810D103 | 195,443 | 2,561,846 | SH | SOLE | 2,561,846 | 0 | 0 | ||
Slack Technologies Inc | Common Stock | 83088V102 | 192 | 4,735 | SH | SOLE | 4,735 | 0 | 0 | ||
TCS Group Holding PLC | GDR | 87238U203 | 77,375 | 1,334,047 | SH | SOLE | 1,334,047 | 0 | 0 | ||
Phreesia Inc | Common Stock | 71944F106 | 66,517 | 1,276,726 | SH | SOLE | 1,276,726 | 0 | 0 | ||
Virgin Galactic Holdings Inc | Common Stock | 92766K106 | 52,919 | 1,727,671 | SH | SOLE | 1,727,671 | 0 | 0 | ||
Workhorse Group Inc | Common Stock | 98138J206 | 55,072 | 3,999,408 | SH | SOLE | 3,999,408 | 0 | 0 | ||
Adyen NV | ADR | 00783V104 | 81,003 | 1,810,940 | SH | SOLE | 1,810,940 | 0 | 0 | ||
Cie Generale des Etablissements Michelin SCA | Common Stock | F61824144 | 5,408 | 36,059 | SH | SOLE | 36,059 | 0 | 0 | ||
voestalpine AG | Common Stock | A9101Y103 | 721 | 17,367 | SH | SOLE | 17,367 | 0 | 0 | ||
Yeahka Ltd | Common Stock | G9835C108 | 87,478 | 12,712,000 | SH | SOLE | 12,712,000 | 0 | 0 | ||
Accolade Inc | Common Stock | 00437E102 | 240,774 | 5,306,902 | SH | SOLE | 5,306,902 | 0 | 0 | ||
Berkeley Lights Inc | Common Stock | 084310101 | 256,976 | 5,115,992 | SH | SOLE | 5,115,992 | 0 | 0 | ||
Vertex Pharmaceuticals Inc | Common Stock | 92532F100 | 369,406 | 1,719,046 | SH | SOLE | 1,719,046 | 0 | 0 | ||
BYD Co Ltd | ADR | 05606L100 | 53,408 | 1,234,435 | SH | SOLE | 1,234,435 | 0 | 0 | ||
Biondvax Pharmaceuticals Ltd | ADR | 09073Q105 | 37 | 9,778 | SH | SOLE | 9,778 | 0 | 0 | ||
Kamada Ltd | Common Stock | M6240T109 | 5,288 | 866,366 | SH | SOLE | 866,366 | 0 | 0 | ||
BATM Advanced Communications Ltd | Common Stock | M19199112 | 5,526 | 4,174,208 | SH | SOLE | 4,174,208 | 0 | 0 | ||
Gamida Cell Ltd | Common Stock | M47364100 | 5,423 | 670,324 | SH | SOLE | 670,324 | 0 | 0 | ||
Gilat Satellite Networks Ltd | Common Stock | M51474118 | 6,852 | 655,093 | SH | SOLE | 655,093 | 0 | 0 | ||
PolyPid Ltd | Common Stock | M8001Q118 | 5,292 | 577,747 | SH | SOLE | 577,747 | 0 | 0 | ||
Silicom Ltd | Common Stock | M84116108 | 6,221 | 137,871 | SH | SOLE | 137,871 | 0 | 0 | ||
Nintendo Co Ltd | ADR | 654445303 | 442,706 | 6,252,905 | SH | SOLE | 5,562,959 | 545,522 | 144,424 | ||
Organovo Holdings Inc | Common Stock | 68620A203 | 5,844 | 606,221 | SH | SOLE | 602,693 | 3,528 | 0 | ||
Surface Oncology Inc | Common Stock | 86877M209 | 31,740 | 4,069,255 | SH | SOLE | 4,069,255 | 0 | 0 | ||
Takeda Pharmaceutical Co Ltd | ADR | 874060205 | 341,775 | 18,717,144 | SH | SOLE | 18,717,144 | 0 | 0 | ||
Niu Technologies | ADR | 65481N100 | 68,264 | 1,862,592 | SH | SOLE | 1,862,592 | 0 | 0 | ||
Thermo Fisher Scientific Inc | Common Stock | 883556102 | 110,349 | 241,791 | SH | SOLE | 241,791 | 0 | 0 | ||
Exact Sciences Corp | Common Stock | 30063P105 | 1,205,607 | 9,148,635 | SH | SOLE | 8,404,723 | 594,597 | 149,315 | ||
Snowflake Inc | Common Stock | 833445109 | 22 | 98 | SH | SOLE | 98 | 0 | 0 | ||
Unity Software Inc | Common Stock | 91332U101 | 812,174 | 8,096,637 | SH | SOLE | 7,510,902 | 424,492 | 161,243 | ||
Beam Therapeutics Inc | Common Stock | 07373V105 | 382,519 | 4,779,104 | SH | SOLE | 4,779,104 | 0 | 0 | ||
Novartis AG | Common Stock | H5820Q150 | 618,936 | 7,219,265 | SH | SOLE | 6,984,729 | 155,467 | 79,069 | ||
Regeneron Pharmaceuticals Inc | Common Stock | 75886F107 | 576,743 | 1,218,970 | SH | SOLE | 1,155,645 | 60,867 | 2,458 | ||
Repare Therapeutics Inc | Common Stock | 760273102 | 41,695 | 1,358,589 | SH | SOLE | 1,358,589 | 0 | 0 | ||
MarketAxess Holdings Inc | Common Stock | 57060D108 | 16,528 | 33,195 | SH | SOLE | 33,195 | 0 | 0 | ||
Agora Inc | ADR | 00851L103 | 86,283 | 1,716,390 | SH | SOLE | 1,716,390 | 0 | 0 | ||
KE Holdings Inc | ADR | 482497104 | 546,555 | 9,592,049 | SH | SOLE | 8,776,600 | 641,970 | 173,479 | ||
Fastly Inc | Common Stock | 31188V100 | 96,450 | 1,433,563 | SH | SOLE | 1,433,563 | 0 | 0 | ||
Cloudflare Inc | Common Stock | 18915M107 | 66,218 | 942,466 | SH | SOLE | 942,466 | 0 | 0 | ||
Palantir Technologies Inc | Common Stock | 69608A108 | 433,950 | 18,632,471 | SH | SOLE | 17,628,771 | 647,600 | 356,100 | ||
Raven Industries Inc | Common Stock | 754212108 | 53,867 | 1,405,340 | SH | SOLE | 1,405,340 | 0 | 0 | ||
Zoom Video Communications Inc | Common Stock | 98980L101 | 964,624 | 3,002,347 | SH | SOLE | 2,784,682 | 157,985 | 59,680 | ||
Honeywell International Inc | Common Stock | 438516106 | 704 | 3,245 | SH | SOLE | 3,245 | 0 | 0 | ||
Alphabet Inc | Common Stock | 02079K305 | 6 | 3 | SH | SOLE | 3 | 0 | 0 | ||
Roche Holding AG | ADR | 771195104 | 328,770 | 8,105,763 | SH | SOLE | 8,105,763 | 0 | 0 | ||
Sarepta Therapeutics Inc | Common Stock | 803607100 | 138,648 | 1,860,293 | SH | SOLE | 1,860,293 | 0 | 0 | ||
Opendoor Technologies Inc | Common Stock | 683712103 | 246,680 | 11,641,318 | SH | SOLE | 11,641,318 | 0 | 0 | ||
BASE Inc | Common Stock | J0433G101 | 32,554 | 2,260,400 | SH | SOLE | 2,260,400 | 0 | 0 | ||
Kaspi.KZ JSC | GDR | 48581R205 | 10,776 | 151,780 | SH | SOLE | 151,780 | 0 | 0 | ||
908 Devices Inc | Common Stock | 65443P102 | 52,034 | 1,072,866 | SH | SOLE | 1,072,866 | 0 | 0 | ||
Magna International Inc | Common Stock | 559222401 | 62,254 | 707,109 | SH | SOLE | 707,109 | 0 | 0 | ||
Peloton Interactive Inc | Common Stock | 70614W100 | 113,730 | 1,011,477 | SH | SOLE | 1,011,477 | 0 | 0 | ||
Veeva Systems Inc | Common Stock | 922475108 | 219,052 | 838,508 | SH | SOLE | 838,508 | 0 | 0 | ||
Grayscale Ethereum Trust | Open-End Fund | 389638107 | 11,433 | 639,069 | SH | SOLE | 0 | 639,069 | 0 | ||
Bristol-Myers Squibb Co | Common Stock | 110122108 | 137,618 | 2,179,919 | SH | SOLE | 2,179,919 | 0 | 0 | ||
SPDR S&P 500 ETF Trust | ETP | 78462F103 | 22 | 55 | SH | SOLE | 55 | 0 | 0 | ||
1Life Healthcare Inc | Common Stock | 68269G107 | 42,920 | 1,098,269 | SH | SOLE | 1,098,269 | 0 | 0 | ||
PyroGenesis Canada Inc | Common Stock | 74734T104 | 1,420 | 211,000 | SH | SOLE | 211,000 | 0 | 0 | ||
Arad Ltd | Common Stock | M1492B104 | 5,688 | 395,760 | SH | SOLE | 395,760 | 0 | 0 | ||
Augwind Energy Tech Storage Ltd | Common Stock | M6058P108 | 4,505 | 193,616 | SH | SOLE | 193,616 | 0 | 0 | ||
Bet Shemesh Engines Holdings 1997 Ltd | Common Stock | M20119109 | 5,894 | 278,364 | SH | SOLE | 278,364 | 0 | 0 | ||
Electra Consumer Products 1970 Ltd | Common Stock | M3798N105 | 6,827 | 158,105 | SH | SOLE | 158,105 | 0 | 0 | ||
E&M Computing Ltd | Common Stock | M4026X105 | 8,659 | 1,213,008 | SH | SOLE | 1,213,008 | 0 | 0 | ||
Ham-Let Israel-Canada Ltd | Common Stock | M5257K100 | 6,094 | 318,886 | SH | SOLE | 318,886 | 0 | 0 | ||
Intercure Ltd | Common Stock | M549GJ103 | 8,376 | 5,139,550 | SH | SOLE | 5,139,550 | 0 | 0 | ||
Itamar Medical Ltd | Common Stock | M61483109 | 5,167 | 6,710,537 | SH | SOLE | 6,710,537 | 0 | 0 | ||
Magic Software Enterprises Ltd | Common Stock | 559166103 | 5,139 | 331,141 | SH | SOLE | 331,141 | 0 | 0 | ||
Malam - Team Ltd | Common Stock | M87437105 | 6,201 | 219,895 | SH | SOLE | 219,895 | 0 | 0 | ||
Plasson Industries Ltd | Common Stock | M7933B108 | 5,755 | 120,887 | SH | SOLE | 120,887 | 0 | 0 | ||
RoboGroup T.E.K Ltd | Common Stock | M20330102 | 4,615 | 2,674,171 | SH | SOLE | 2,674,171 | 0 | 0 | ||
Desktop Metal Inc | Common Stock | 25058X105 | 15,355 | 1,030,570 | SH | SOLE | 1,030,570 | 0 | 0 | ||
DarioHealth Corp | Common Stock | 23725P209 | 5,231 | 271,619 | SH | SOLE | 271,619 | 0 | 0 | ||
Enlivex Therapeutics Ltd | Common Stock | M4130Y106 | 5,283 | 476,414 | SH | SOLE | 476,414 | 0 | 0 | ||
Experience Investment Corp | Common Stock | 30217C208 | 30,799 | 2,744,999 | SH | SOLE | 2,744,999 | 0 | 0 | ||
JFrog Ltd | Common Stock | M6191J100 | 4,040 | 91,060 | SH | SOLE | 91,060 | 0 | 0 | ||
Eastman Kodak Co | Common Stock | 277461406 | 575 | 73,084 | SH | SOLE | 73,084 | 0 | 0 | ||
Kornit Digital Ltd | Common Stock | M6372Q113 | 6,053 | 61,070 | SH | SOLE | 61,070 | 0 | 0 | ||
Lockheed Martin Corp | Common Stock | 539830109 | 102,261 | 276,755 | SH | SOLE | 276,755 | 0 | 0 | ||
Nano-X Imaging Ltd | Common Stock | M70700105 | 3,898 | 94,053 | SH | SOLE | 94,053 | 0 | 0 | ||
PACCAR Inc | Common Stock | 693718108 | 293,409 | 3,157,652 | SH | SOLE | 2,724,925 | 344,432 | 88,295 | ||
SolarEdge Technologies Inc | Common Stock | 83417M104 | 5,300 | 18,439 | SH | SOLE | 18,439 | 0 | 0 | ||
Skillz Inc | Common Stock | 83067L109 | 114,473 | 6,012,260 | SH | SOLE | 6,012,260 | 0 | 0 | ||
Teledyne Technologies Inc | Common Stock | 879360105 | 88,925 | 214,977 | SH | SOLE | 214,977 | 0 | 0 | ||
Twitter Inc | Common Stock | 90184L102 | 495,884 | 7,793,240 | SH | SOLE | 7,082,389 | 585,409 | 125,442 | ||
AbbVie Inc | Common Stock | 00287Y109 | 59,858 | 553,117 | SH | SOLE | 553,117 | 0 | 0 | ||
Butterfly Network Inc | Common Stock | 124155102 | 88,969 | 5,286,325 | SH | SOLE | 5,286,325 | 0 | 0 | ||
CM Life Sciences Inc | Common Stock | 18978W109 | 63,008 | 4,231,546 | SH | SOLE | 4,231,546 | 0 | 0 | ||
Signify Health Inc | Common Stock | 82671G100 | 49,567 | 1,694,034 | SH | SOLE | 1,694,034 | 0 | 0 | ||
ARK Innovation ETF | ETP | 00214Q104 | 2,171 | 18,101 | SH | SOLE | 18,101 | 0 | 0 | ||
Ping An Healthcare and Technology Co Ltd | Common Stock | G71139102 | 50,296 | 4,010,500 | SH | SOLE | 4,010,500 | 0 | 0 | ||
Bill.com Holdings Inc | Common Stock | 090043100 | 24,605 | 169,108 | SH | SOLE | 169,108 | 0 | 0 | ||
DraftKings Inc | Common Stock | 26142R104 | 268,345 | 4,375,424 | SH | SOLE | 4,227,724 | 93,000 | 54,700 | ||
Atlas Crest Investment Corp | Common Stock | 049284102 | 14,668 | 1,459,498 | SH | SOLE | 1,459,498 | 0 | 0 | ||
One | Common Stock | G7000X105 | 24,385 | 2,103,928 | SH | SOLE | 2,103,928 | 0 | 0 | ||
Vuzix Corp | Common Stock | 92921W300 | 53,017 | 2,084,017 | SH | SOLE | 2,084,017 | 0 | 0 | ||
ARK Genomic Revolution ETF | ETP | 00214Q302 | 953 | 10,735 | SH | SOLE | 10,735 | 0 | 0 | ||
Seer Inc | Common Stock | 81578P106 | 42,431 | 848,274 | SH | SOLE | 848,274 | 0 | 0 | ||
iShares Russell 1000 Growth ETF | ETP | 464287614 | 795 | 3,270 | SH | SOLE | 3,270 | 0 | 0 | ||
Airbus SE | Common Stock | N0280G100 | 1,013 | 8,928 | SH | SOLE | 8,928 | 0 | 0 | ||
Thales SA | Common Stock | F9156M108 | 2,512 | 25,234 | SH | SOLE | 25,234 | 0 | 0 | ||
Komatsu Ltd | Common Stock | J35759125 | 2,880 | 93,188 | SH | SOLE | 93,188 | 0 | 0 | ||
Boeing Co/The | Common Stock | 097023105 | 2,290 | 8,990 | SH | SOLE | 8,990 | 0 | 0 | ||
Garmin Ltd | Common Stock | H2906T109 | 1,292 | 9,797 | SH | SOLE | 9,797 | 0 | 0 | ||
HEICO Corp | Common Stock | 422806109 | 724 | 5,756 | SH | SOLE | 5,756 | 0 | 0 | ||
L3Harris Technologies Inc | Common Stock | 502431109 | 3,164 | 15,613 | SH | SOLE | 15,613 | 0 | 0 | ||
The 3D Printing ETF | ETP | 00214Q500 | 3,891 | 100,170 | SH | SOLE | 100,170 | 0 | 0 | ||
ROBLOX Corp | Common Stock | 771049103 | 33,509 | 516,877 | SH | SOLE | 516,877 | 0 | 0 | ||
Reinvent Technology Partners | Common Stock | G7483N129 | 457 | 45,000 | SH | SOLE | 45,000 | 0 | 0 | ||
Jaws Spitfire Acquisition Corp | Common Stock | G50740102 | 8,164 | 796,478 | SH | SOLE | 796,478 | 0 | 0 | ||
Spirit AeroSystems Holdings Inc | Common Stock | 848574109 | 2,046 | 42,063 | SH | SOLE | 42,063 | 0 | 0 |